Description
YAP1 monoclonal Antibody | MB65692 | Gentaur UK, US & Europe Distribution
Host: Mouse
Reactivity: Human, Mouse
Application: WB
Application Range: WB 1:1000
Background: This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013]
Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: Yes associated protein 1
Molecular Weight: 54.3 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: COB1; YAP; YAP2; YAP65; YKI
Immunogen: Human recombinant protein fragment corresponding to amino acids 347-504 of human YAP1 (NP_001123617) produced in E.coli.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A