YB1 (phospho Ser102) Antibody | 79-928

YB1 (phospho Ser102) Antibody | 79-928 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: YB1 (phospho Ser102) antibody was raised against a peptide sequence around phosphorylation site of Serine 102 (L-R-S (p) -V-G) derived from Human YB1.

Research Area: Phospho-Specific

Tested Application: WB

Application: Western Blot: 1:500~1:1000

Specificiy: The antibody detects endogenous levels of YB1 only when phosphorylated at serine 102.

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 36 kDa

Validation: N/A

Isoform: N/A

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+) , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Concentration: 1 mg/mL

Storage Condition: Store antibody at -20˚C for up to one year.

Alternate Name: CBF-A, NSEP1, EFI-A, MSY-1, YBX1

User Note: N/A

BACKGROUND: YB-1 is a nuclear protein that binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors CCAAT-containing Y-box of HLA class II genes. Component of cytoplasmic messenger ribonucleoprotein particles (mRNPs) . Interacts with AKT1, SFRS9, THOC4, MSH2, XRCC5, WRN and NCL. Can bind to DNA as a homomeric form, (EFI-A) n or as a heteromeric form in association with EFI-B. Homodimer in the presence of ATP.