YPEL4 Antibody | 6777

YPEL4 Antibody | 6777 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: Predicted species reactivity based on immunogen sequence: Rat: (100%)

Immunogen: YPEL4 antibody was raised against a 12 amino acid synthetic peptide near the amino terminus of human YPEL4.
The immunogen is located within the first 50 amino acids of YPEL4.

Research Area: Cancer, Cell Cycle

Tested Application: E, WB, ICC, IF

Application: YPEL4 antibody can be used for detection of YPEL4 by Western blot at 1 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Specificiy: N/A

Positive Control 1: Cat. No. 1221 - SW480 Cell Lysate

Positive Control 2: Cat. No. 17-207 - EL4 Cell Slide

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: YPEL4 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: YPEL4 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: YPEL4 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: YPEL4 Antibody: Protein yippee-like 4

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: YPEL4 Antibody: YPEL4 (yippee-like 4) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division. YPEL4 is ubiquitously expressed in adult tissues and has been shown to associate with the major vault protein (MVP) . It has been suggested that MVP can inhibit YPEL4's ability to activate Elk-1 in the MAPK signaling pathway.