Description
YWHAZ Antibody | 13-067 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse
Homology: N/A
Immunogen: A synthetic peptide of human YWHAZ
Research Area: Apoptosis, Cell Cycle, Immunology, Neuroscience, Signal Transduction
Tested Application: WB, IHC, Flow
Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:100
Flow: 1:20 - 1:50
Specificiy: N/A
Positive Control 1: Mouse brain
Positive Control 2: SH-SY5Y
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 30kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, pH7.3.
Concentration: N/A
Storage Condition: Store at 4˚C. Avoid freeze / thaw cycles.
Alternate Name: YWHAZ, KCIP-1, MGC111427, MGC126532, MGC138156, HEL4, YWHAD, HEL-S-3, 14-3-3-zeta
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.