YY1 Polyclonal Antibody | E-AB-18318

YY1 Polyclonal Antibody | E-AB-18318 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: CF1, Delta, Delta transcription factor, INO80 complex subunit S, INO80S, NF E1, NF-E1, NFE1, OTTHUMP00000197459, Transcriptional repressor protein YY1, TYY1, UCR motif DNA binding protein, UCRBP, Yin and yang 1, Yin and Yang 1 protein, Yin Yang 1, Ying Yang 1, YY 1, YY 1 transcription factor, YY-1, YY1, YY1 transcription factor

Application: WB, IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Epigenetics and Nuclear Signaling, Neuroscience

Background: YY1, also named as DELTA, INO80S and NF-E1, contains four C2H2-type zinc fingers and belongs to the YY transcription factor family. YY1 is a multifunctional transcription factor that exhibits positive and negative control on a large number of cellular and viral genes by binding to sites overlapping the transcription start site. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the YY1. The open reading frame of the human YY1 cDNA encodes a protein of 414 amino acids with a predicted molecular weight of 44 kDa. However, YY1 migrates on SDS gels as a 65–68 kDa protein, probably due to the structure of the protein. It is a ubiquitously expressed transcription factor with fundamental roles in embryogenesis, differentiation, replication and proliferation.

Concentration: 0.9 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human YY1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 45 kDa

Molecular Weight(Observed): Refer to figures