(Z)-4-Hydroxytamoxifen | B1114

(Z)-4-Hydroxytamoxifen is a metabolite of Tamoxifen (Cat. No. 1551); acts as a potent estrogen receptor antagonist. Displays more potency than the parent compound. Also activates intein-linked inactive Cas9, reducing off-target CRISPR-mediated gene editing.

(Z)-4-Hydroxytamoxifen is a metabolite of Tamoxifen (Cat. No. 1551); acts as a potent estrogen receptor antagonist. Displays more potency than the parent compound. Also activates intein-linked inactive Cas9, reducing off-target CRISPR-mediated gene editing.

B1114 | (Z)-4-Hydroxytamoxifen DataSheet

Alternate Name/Synonyms: 4-[(1Z)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol; 4-OH-TAM

Appearance: White solid

Formulation: N/A

CAS Number: 68047-06-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₆H₂₉NO₂

Molecular Weight: 387.51

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>35 mg/ml) or H2O (>10 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent estrogen receptor antagonist and Cas9 activator

MDL Number: MFCD00278780

PubChem CID: 449459

SMILES: CCC(=C(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3

InChi: InChI=1S/C26H29NO2/c1-4-25(20-8-6-5-7-9-20)26(21-10-14-23(28)15-11-21)22-12-16-24(17-13-22)29-19-18-27(2)3/h5-17,28H,4,18-19H2,1-3H3/b26-25-

InChi Key: TXUZVZSFRXZGTL-QPLCGJKRSA-N