Z-VEID-FMK | 1146

VEID is the specific recognition sequence for caspase-6/Mch2. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).

Z-VEID-FMK is a cell-permeable, irreversible caspase-6 inhibitor.

1146 | Z-VEID-FMK DataSheet

Alternate Name/Synonyms: Z-VEID-FMK, Z-VEID-fluoromethylketone, Caspase-6 Inhibitor (fluoromethylketone)

Appearance: Lyophilized solid

Formulation: N/A

CAS Number: N/A

Structure Available?: No

Peptide sequence: Z-Val-E(OMe)-Ile-Asp(OMe)-FMK

Salt Form: No

Molecular Formula: C₃₁H₄₅FN₄O₁₀

Molecular Weight: 652.9

Cell-Permeable?: Yes

Purity: Single spot by TLC

Solubilities: DMSO (20 mM)

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A caspase-6 inhibitor

MDL Number: N/A

PubChem CID: 44135214

SMILES: CCC(C)C(C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)C(CCC(=O)OC)NC(=O)C(C(C)C)NC(=O)OCC1=CC=CC=C1

InChi: InChI=1S/C31H45FN4O10/c1-7-19(4)27(30(42)34-22(23(37)16-32)15-25(39)45-6)35-28(40)21(13-14-24(38)44-5)33-29(41)26(18(2)3)36-31(43)46-17-20-11-9-8-10-12-20/h8-12,18-19,21-22,26-27H,7,13-17H2,1-6H3,(H,33,41)(H,34, 42)(H,35,40)(H,36,43)

InChi Key: YPIHFMWAHMPACV-UHFFFAOYSA-N