ZBTB48 polyclonal Antibody | BS91463

ZBTB48 polyclonal Antibody | BS91463 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB ICC IHC FC

Application Range: WB:1:500-1:1,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:200

Background: Telomere-binding protein that acts as a regulator of telomere length. Directly binds the telomeric double-stranded 5'-TTAGGG-3' repeat. Preferentially binds to telomeres that have a low concentration of shelterin complex and acts as a regulator of telomere length by initiating telomere trimming, a process that prevents the accumulation of aberrantly long telomeres. Also acts as a transcription regulator that binds to promoter regions. Regulates expression of a small subset of genes, including MTFP1. Regulates expression the J and/or S elements in MHC II promoter. Acts as a negative regulator of cell proliferation by specifically activating expression of ARF, a tumor suppressor isoform of CDKN2A.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: ZBTB48 polyclonal Antibody detects endogenous levels of ZBTB48 protein.

Molecular Weight: 77 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: TZAP, hKR3, ZBTB48, HKR3, TZAP, ZNF855, 0610011D15Rik, AI327031, GLI Kruppel family member HKR3, HKR3, Krueppel related zinc finger protein 3, Krueppel-related zinc finger protein 3, OTTMUSP00000031803, pp9964, Protein HKR3, RP23-445E20.3, ZBT48, ZBTB 48, Zbtb48, Zinc finger and BTB domain containing 48, Zinc finger and BTB domain containing protein 48, Zinc finger and BTB domain-containing protein 48, Zinc finger protein 855, ZNF855,

Immunogen: Peptide

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Peptide affinity purified

Pathway: