ZC3H12A (CT) Antibody | 9547

ZC3H12A (CT) Antibody | 9547 | Gentaur UK, US & Europe Distribution

Product Type: Primary Antibodies

Research Area: Innate Immunity

Host Species: Rabbit

Species Reactivity: Human, Mouse, Rat

Homology: Predicted species reactivity based on immunogen sequence: Chimpanzee (100%) ; Monkey (100%) ; Pig (79%) ; Chicken (83%)

Immunogen: Anti-ZC3H12A antibody (9547) was raised against a peptide corresponding to 14 amino acids near the carboxyl terminus of human ZC3H12A.

The immunogen is located within the last 50 amino acids of ZC3H12A.

Tested Application: E, WB, IF, IHC

Predicted MW: Predicted: 66 kD
Observed: 66 kD

Purification: ZC3H12A Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: ZC3H12A Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage: ZC3H12A antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Additional Names: ZC3H12A Antibody: Endoribonuclease ZC3H12A, Monocyte chemotactic protein-induced protein 1, MCP-induced protein 1, MCPIP-1, Zinc finger CCCH domain-containing protein 12A

Background: ZC3H12A Antibody: ZC3H12A is an MCP1 (CCL2; MIM 158105) -induced protein that acts as a transcriptional activator and causes cell death of cardiomyocytes, possibly via induction of genes associated with apoptosis. ZC3H12A inhibits the Wnt/beta-catenin signaling pathway activity and modulates epithelial-mesenchymal transition during clear cell renal cell carcinoma progression by targeting miRNAs. ZC3H12A ribonuclease can bind and cleave AURKA mRNA in MYCN-amplified neuroblastoma cells. ZC3H12A is a novel link between diabetogenic conditions and impaired insulin secretory capacity. ZC3H12A overexpression in human neuroblastoma cell lines causes cell-cycle arrest by G1/S checkpoint block.

Shipping Condition: Blue Ice

Source: N/A

Species: N/A

Peptide Location: N/A

By Source: N/A

By Species: N/A

Recombinant Protein Sequence: N/A

Badges: Trial Size, New