ZFP42 Polyclonal Antibody | E-AB-13003

ZFP42 Polyclonal Antibody | E-AB-13003 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: hREX-1, Reduced Expression 1 Protein, Reduced expression protein 1, Rex-1, REX1, REX1 transcription factor, Zfp-42, Zfp42, ZFP42 zinc finger protein, ZFP42, Zinc finger protein 42 homolog, Zinc finger protein 754, ZNF754

Application: WB, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Developmental Biology, Stem Cells

Background: Rex-1 (for reduced expression), also designated zinc finger protein 42 (ZFP42), is an acidic zinc finger protein. Rex-1 contains four repeats of the zinc finger nucleic acid-binding motif and a potential acidic activator domain, suggesting that it is a regulatory protein. Rex-1 localizes to the nucleus and is highly expressed in embryonic stem (ES) and undifferentiated murine F9 teratocarcinoma cells. At the transcriptional level, expression of Rex-1 is reduced when F9 cells are induced to differentiate by the addition of retinoic acid (RA), and Rex-1 repression is enhanced by E1A. The Oct-3/4 transcription factor can either activate or repress the Rex-1 promoter, depending on the cellular environment, while Oct-6 can lower the expression of Rex-1.

Concentration: 0.3 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human ZFP42

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 35 kDa

Molecular Weight(Observed): N/A