ZKSCAN3 Antibody (N-Term) [APR33346G]

ZKSCAN3 Antibody (N-Term) [APR33346G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This ZKSCAN3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 100-130 amino acids from human ZKSCAN3.

Cellular Localisation: Nucleus. Cytoplasm. Note=Mainly localizes in the nucleus. Under starvation conditions translocates to the cytoplasm, allowing expression of target genes involved in autophagy and lysosome biogenesis/function

Molecular Weight: 60641

Clone: Polyclonal

Gene Name: ZKSCAN3

Gene ID: 80317

Function: Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migration in various tumors and myelomas.

Summary: N/A

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Zinc finger protein with KRAB and SCAN domains 3, Zinc finger and SCAN domain-containing protein 13, Zinc finger protein 306, Zinc finger protein 309, Zinc finger protein 47 homolog, Zf47, Zfp-47, ZKSCAN3, ZFP47, ZNF306, ZNF309, ZSCAN13