ZKSCAN3 Polyclonal Antibody | E-AB-18451

ZKSCAN3 Polyclonal Antibody | E-AB-18451 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: dJ874C20.1, mszf35, SCAN-KRAB-zinc finger protein, Skz1, Zf47, Zfp-47, ZFP306, Zfp307, Zfp47, Zinc finger and SCAN domain containing protein 13, Zinc finger and SCAN domain-containing protein 13, Zinc finger protein 306, Zinc finger protein 306, isoform CRA_a, Zinc finger protein 307, Zinc finger protein 309, Zinc finger protein 47 homolog, Zinc finger protein with KRAB and SCAN domains 3, Zinc finger protein with KRAB and SCAN domains 3, Zinc finger protein zfp47 , Zinc finger with KRAB and SCAN domains 3, ZKSC3, ZKSCAN3, ZNF309, ZSCAN13, ZSCAN35

Application: IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Epigenetics and Nuclear Signaling

Background: Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migation in various tumors and myelomas.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human ZKSCAN3

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:40-1:250, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A