ZMYM4 Antibody | 6139

ZMYM4 Antibody | 6139 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: Predicted species reactivity based on immunogen sequence: Mouse: (94%)

Immunogen: ZMYM4 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human ZMYM4.
The immunogen is located within the last 50 amino acids of ZMYM4.

Research Area: Cancer, Cell Cycle

Tested Application: E, IHC-P

Application: ZMYM4 antibody can be used for detection of ZMYM4 by immunohistochemistry at 5 μg/mL.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.

Specificiy: At least three isoforms of ZMYM4 are known to exist; this antibody will detect all of them. ZMYM4 antibody is predicted not to cross-react with other ZMYM family members.

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 167 kDa

Validation: N/A

Isoform: N/A

Purification: ZMYM4 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: ZMYM4 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: ZMYM4 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: ZMYM4 Antibody: MYM, CDIR, ZNF262, ZNF198L3, KIAA0425, Zinc finger MYM-type protein 4, Zinc finger protein 262

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: ZMYM4 Antibody: Zinc-finger proteins contain DNA-binding domains characterized by the unique role of zinc and have a wide variety of functions such as transcriptional activation or repression. The protein folding and the DNA binding ability are governed by the coordination of a zinc ion. It has been found to be overexpressed in human lung adenocarcinomas and squamous cell carcinomas, and the overexpression of a fragment of the 3'UTR of the ZMYM4 mRNA termed Cell Death Inhibiting RNA (CDIR) protects HeLa cells from IFN-γ-induced apoptosis, suggesting that ZMYM4 may play a role in tumorigenesis.