ZnAF-2, 6-Iso | 2756

ZnAF-2, 6-iso-, is a cell-impermeable compound that acts as a high-affinity Zn²⁺-specific fluorescent probe (Kd = 2.7 nM). It shows low basal fluorescence and the fluorescence intensity increases ~51-fold upon stoichiometric (1:1) binding to Zn²⁺. Exhibits little affinity towards Ca²⁺, Mg²⁺, Na⁺, or K⁺.

ZnAF-2, 6-iso-, is a cell-impermeable compound that acts as a high-affinity Zn²⁺-specific fluorescent probe (Kd = 2.7 nM). It shows low basal fluorescence and the fluorescence intensity increases ~51-fold upon stoichiometric (1:1) binding to Zn²⁺. Exhibits little affinity towards Ca²⁺, Mg²⁺, Na⁺, or K⁺.

2756 | ZnAF-2, 6-Iso DataSheet

Alternate Name/Synonyms: 6-{2-[Bis(2-pyridylmethyl)amino]ethylamino}fluorescein

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 321859-11-4

Structure Available?: Y

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₃₄H₂₈N₄O₅

Molecular Weight: 572.61

Cell-Permeable?: Yes

Purity: ≥95% by HPCE

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A fluorescent Zinc probe

MDL Number: MFCD08277015

PubChem CID: 16218345

SMILES: C1=CC=NC(=C1)CN(CCNC2=CC(=C(C=C2)C(=O)O)C3=C4C=CC(=O)C=C4OC5=C3C=CC(=C5)O)CC6=CC=CC=N6

InChi: InChI=1S/C34H28N4O5/c39-25-8-11-28-31(18-25)43-32-19-26(40)9-12-29(32)33(28)30-17-22(7-10-27(30)34(41)42)37-15-16-38(20-23-5-1-3-13-35-23)21-24-6-2-4-14-36-24/h1-14,17-19,37,39H,15-16,20-21H2,(H,41,42)

InChi Key: CORIVNRIBACDOQ-UHFFFAOYSA-N