Description
ZNF187 polyclonal Antibody | BS5945 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB ICC
Application Range: WB: 1:500~1:1000 ICC: 1:50~1:200
Background: The best studied of the immediate early genes is the c-Fos proto-oncogene. Many of the signals inducing Fos expression act through a sequence located in the 5' flanking region of c-Fos, designated the serum response element (SRE) . The SRE is required for response to activators of protein kinase C and Fos growth-induced signals independent of protein kinase C. Accumulating evidence argues that the SRE is a multifunctional element that may involve the action of multiple SRE-binding proteins. These include the serum response factor (SRF) and the two less well characterized proteins, TCF p62 and BBF p62. An SRE binding nuclear protein, designated SRE-ZBP, is a member of the C2H2 zinc finger family of proteins. Like c-Fos, SRE-ZBP is serum-inducible in HeLa cells, although with slower kinetics.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ZNF187 polyclonal Antibody detects endogenous levels of ZNF187 protein.
Molecular Weight: ~ 55 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Zinc finger and SCAN domain-containing protein 26; Protein SRE-ZBP; Zinc finger protein 187; ZSCAN26
Immunogen: Synthetic peptide, corresponding to amino acids 149-194 of Human ZNF187.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: