BW
ZNF318 Polyclonal Antibody | BS65684
- SKU:
- BW-BS65684
- Availability:
- Usually ships in 5 working days
Description
ZNF318 Polyclonal Antibody | BS65684 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat,Dog,Pig,Horse,Rabbit,
Application: WB,IHC-P,
Application Range: WB=1:500-2000 IHC-P=1:100-500
Background: ZNF318 is a 2279 amino acid endocrine regulatory protein that localizes to the nucleus. Highly expressed in testis, ovaries and kidneys, ZNF318 is a co-repressor of androgen receptor (AR) -mediated transcriptional activation and is thought to regulate transcription during spermatogenesis. ZNF318 interacts with the N-terminal domain of AR and contains two matrin-type zinc fingers. Two isoforms of ZNF318, designated TZF and TZF-L, are produced due to alternative splicing events. Each of these splice variants are thought to have unique roles in transcriptional regulation. While the TZF isoform functions as a repressor of AR-mediated transcriptional activation, the TZF-L isoform is thought to enhance AR-mediated transcriptional activation.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ZNF318 Polyclonal Antibody detects endogenous levels of ZNF318 protein.
Molecular Weight: 125 kD
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Endocrine Regulatory Protein; HGNC13578; HRIHFB2436; ZFP318; Zinc Finger Protein 318; ZN318_HUMAN.
Immunogen: KLH conjugated synthetic peptide derived from human ZNF318
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: affinity purified by Protein A
Pathway: