ZNF322B Antibody (C-term) [APR30453G]

ZNF322B Antibody (C-term) [APR30453G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This ZNF322B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 326-354 amino acids from the C-terminal region of human ZNF322B.

Cellular Localisation: Cytoplasm. Nucleus. Note=Mainly found in the nucleus

Molecular Weight: 46941

Clone: Polyclonal

Gene Name: ZNF322

Gene ID: 79692

Function: Transcriptional activator (PubMed:15555580) . Important for maintenance of pluripotency in embryonic stem cells (By similarity) . Binds directly to the POU5F1 distal enhancer and the NANOG proximal promoter, and enhances expression of both genes (By similarity) . Can also bind to numerous other gene promoters and regulates expression of many other pluripotency factors, either directly or indirectly (By similarity) . Promotes inhibition of MAPK signaling during embryonic stem cell differentiation (By similarity) .

Summary: Tissue Location: Ubiquitous. Highly expressed in heart and skeletal muscle.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Zinc finger protein 322, Zinc finger protein 322A, Zinc finger protein 388, Zinc finger protein 489, ZNF322, ZNF322A, ZNF388, ZNF489