ZNF395 Polyclonal Antibody | E-AB-13288

ZNF395 Polyclonal Antibody | E-AB-13288 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: DKFZp434K1210, HD gene regulatory region binding protein 2, HD gene regulatory region-binding protein 2, HD-regulating factor 2, HDBP-2, HDBP2, HDRF-2, Huntington disease gene regulatory region-binding protein 2, Huntington's disease gene regulatory region binding protein 2, Papillomavirus regulatory factor 1, papillomavirus regulatory factor PRF 1, Papillomavirus-binding factor, PBF, PRF-1, PRF1, PTTG1IP, Si-1-8-14, Zinc finger protein 395, ZN395, znf395

Application: IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Epigenetics and Nuclear Signaling, Microbiology

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF395 (Zinc finger protein 395), also known as PBF (Papillomavirus-binding factor) and HDBP2 (Huntington disease gene regulatory region-binding protein 2), is a 513 amino acid protein that contains one C2H2-type zinc finger. ZNF395 binds to the 3’-CCGG-5’ sequence within the papillomavirus promoter adjacent to a RUNX1-binding motif. It has also been established that ZNF395 binds to a seven base pair region within the Huntington's disease (HD) gene promoter, an essential element for HD gene expression. ZNF395 is widely expressed and probably shuttles between the nucleus and cytoplasm.

Concentration: 0.8 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human ZNF395

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A