ZNF830 Antibody (Center) [APR04658G]

ZNF830 Antibody (Center) [APR04658G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This ZNF830 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 173-207 amino acids from the Central region of human ZNF830.

Cellular Localisation: Nucleus. Chromosome {ECO:0000250|UniProtKB:Q8R1N0}. Nucleus speckle {ECO:0000250|UniProtKB:Q8R1N0}. Note=Excluded from nucleolus {ECO:0000250|UniProtKB:Q8R1N0}

Molecular Weight: 41999

Clone: Polyclonal

Gene Name: ZNF830 (HGNC:28291)

Gene ID: 91603

Function: May play a role in pre-mRNA splicing as component of the spliceosome (PubMed:25599396) . Acts as an important regulator of the cell cycle that participates in the maintenance of genome integrity. During cell cycle progression in embryonic fibroblast, prevents replication fork collapse, double-strand break formation and cell cycle checkpoint activation. Controls mitotic cell cycle progression and cell survival in rapidly proliferating intestinal epithelium and embryonic stem cells. During the embryo preimplantation, controls different aspects of M phase. During early oocyte growth, plays a role in oocyte survival by preventing chromosomal breaks formation, activation of TP63 and reduction of transcription (By similarity) .

Summary: N/A

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Zinc finger protein 830, Coiled-coil domain-containing protein 16, ZNF830, CCDC16