Description
ZWILCH Polyclonal Antibody | E-AB-53208 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: FLJ10036, FLJ16343, homolog of Drosophila Zwilch, hZwilch, KNTC1AP, MGC111034, Protein zwilch homolog, ZWILC, zwilch, zwilch kinetochore protein, ZWILCH protein, Zwilch, kinetochore associated, homolog
Application: WB, ELISA
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: Cell Biology
Background: This protein is essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. And it is required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. ZWILCH gene is deleted in a patient suffering from colorectal cancer with chromosomal instability.
Concentration: 0.6 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human ZWILCH
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: WB 1:1000-1:5000, ELISA 1:2000-1:10000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 67 kDa
Molecular Weight(Observed): Refer to figures