Zyxin polyclonal Antibody | BS91467

Zyxin polyclonal Antibody | BS91467 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Application: WB ICC/IF IHC FC IP

Application Range: WB:1:500-1:1,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100

Background: Zyxin is a low abundance phosphoprotein localized to focal adhesion plaques and is thought to perform regulatory functions at these regions. The protein contains a number of proline-rich sequences as well as three LIM domains, zinc finger domains involved in protein binding. Zyxin interacts with several other proteins at cell adhesion sites, including members of the CRP (cysteine-rich protein) LIM domain containing protein family. The proline-rich domain of Zyxin associates with an SH3 domain of p95 Vav, but not with similar SH3 domains containing proteins such as GRB2 or PLCg. Zyxin has also been shown to interact with the focal adhesion protein VASP and may assist in the targeting of VASP to focal adhesions, microfilaments and membrane regions of high dynamic activity.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: Zyxin polyclonal Antibody detects endogenous levels of Zyxin protein.

Molecular Weight: 75/61/45 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: ZYX, ESP 2, ESP2, HED 2, HED2, ZYX, ZYX protein, Zyxin 2, Zyxin2,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: