26

K163 | CaspSELECT Caspase-3 Immunoassay Kit Fluorometric DataSheet

A potent inhibitor of α- and β-glucosidases. Exhibits antiviral properties. Inhibits HIV infectivity and thyroglobulin secretion. Displays antitumor and antiangiogenic activity. Also inhibits protein...

Casticin, a polymethoxyflavone, is one of the major active components obtained from Fructus viticis. It displays anticancer activities including induction of cell apoptosis in human cancer cells...

K773 | Catalase Activity Colorimetric/Fluorometric Assay Kit DataSheet

6727 | Catalase Antibody (Center) DataSheet

3806 | Catalase Antibody DataSheet

3806BP | Catalase Blocking Peptide DataSheetAntibody Target: Catalase Accession #: P04040Gene ID: 847Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

Catalase human recombinant | 7362

Composed of four identical subunits each with a molecular weight of 59,700. Catalyzes the reaction 2HO to HO+O. Catalase, along with the superoxides dismutase and glutathione peroxidase, controls the...

CAT is a key antioxidant enzyme in the bodies’ defense against oxidative stress. Also, it is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. CAT converts the reactive...

Catharanthine is one of the alkaloids isolated from the plant Catharanthus roseus. It stimulates the release of amylase from pancreatic fragments and causes extensive degranulation of pancreatic...

CTSA, also known as lysosomal protective protein isoform b, is a component of the lysosomal multienzyme complex along with beta-galactosidase and sialidase Neu1. It is a multicatalytic enzyme with...

Cathepsin B is a lysosomal cysteine protease. It is implicated in playing a role in protein degradation, arthritis, apoptosis, and cancer.1021 | Cathepsin B active human DataSheetBiomolecule/Target:...

K140 | Cathepsin B Activity Fluorometric Assay Kit DataSheet

3190 | Cathepsin B Antibody DataSheet

3190BP | Cathepsin B Blocking Peptide DataSheetAntibody Target: Cathepsin B (for 3190-100) Accession #: P07858Gene ID: 1508Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2...

K147 | Cathepsin B CTSB Inhibitor Screening Kit Fluorometric DataSheet

K7408 | Cathepsin B human Elisa Kit DataSheet

K7407 | Cathepsin B mouse Elisa Kit DataSheet

A potent, cell-permeable, and irreversible inhibitor of Cathepsin B and L.Z-F-FMK is a potent, cell-permeable, and irreversible inhibitor of Cathepsin B and L.1126 | Cathepsin B&L Inhibitor...

Cathepsin D is an estrogen-regulated protein associated with tissue breakdown. Levels of cathepsin D have been positively correlated with recurring breast cancers of both node negative and node...

K143 | Cathepsin D Activity Fluorometric Assay Kit DataSheet

3191R | Cathepsin D Antibody DataSheet

3191RBP | Cathepsin D Blocking Peptide DataSheetAntibody Target: Cathepsin D Accession #: P07711Gene ID: 1514Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in...

K7409 | Cathepsin D human Elisa Kit DataSheet

K148 | Cathepsin D Inhibitor Screening Kit Fluorometric DataSheet

K7410 | Cathepsin D mouse Elisa Kit DataSheet

K165 | Cathepsin E Activity Assay Kit Fluorometric DataSheet

K166 | Cathepsin E Inhibitor Screening Kit Fluorometric DataSheet

3371 | Cathepsin F Antibody DataSheet

3371BP | Cathepsin F Blocking Peptide DataSheetAntibody Target: Cathepsin F Accession #: Q9UBX1Gene ID: 8722Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in...

Cathepsin F, also known as CTSF, belongs to the cathepsin family. Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. The CTSF gene...

K146 | Cathepsin G Activity Colorimetric Assay Kit DataSheet

3370 | Cathepsin G Antibody DataSheet

E4639 | Cathepsin G CTSG Human Elisa Kit DataSheet

E4640 | Cathepsin G CTSG Rat Elisa Kit DataSheet

K162 | Cathepsin G Inhibitor Screening Kit Colorimetric DataSheet

A potent, selective, reversible, competitive, non-peptide inhibitor of cathepsin G (IC₅₀ = 53 nM and Ki = 63 nM). Acts as a weak inhibitor of chymotrypsin (Ki = 1.5 µM), thrombin, factor Xa, factor...

An excellent colorimetric substrate for cathepsin G.An excellent colorimetric substrate for cathepsin G.2206 | Cathepsin G Substrate, Colorimetric DataSheetAlternate Name/Synonyms:...

Cathepsin G is a serine protease secreted by activated neutrophils that play a role in the inflammatory response. This enzyme degrades collagen and proteoglycan and can also cause the release of...

A more basic protein than Cathepsin B or L. Functions as both an aminopeptidase and endopeptidase. Cathepsin H, like cathepsin L and B, is involved in the catabolism of proteins in the lysosomal...

K145 | Cathepsin H Activity Fluorometric Assay Kit DataSheet

K164 | Cathepsin H Inhibitor Screening Kit Fluorometric DataSheet

K141 | Cathepsin K Activity Fluorometric Assay Kit DataSheet

3588 | Cathepsin K Antibody DataSheet

3368BP | Cathepsin K Blocking Peptide DataSheetAntibody Target: Cathepsin K Accession #: NP_113748Gene ID: 29175Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in...

3588BP | Cathepsin K Blocking Peptide DataSheetAntibody Target: Cathepsin K Accession #: NP_113748Gene ID: 29175Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in...

E4620 | Cathepsin K CTSK Human Elisa Kit DataSheet

E4621 | Cathepsin K CTSK Mouse Elisa Kit DataSheet

E4622 | Cathepsin K CTSK Rat Elisa Kit DataSheet

K150 | Cathepsin K Inhibitor Screening Kit Fluorometric DataSheet

Cathepsin K, a member of the papain cysteine proteinase family is the predominant proteinase responsible for the resorption of the bone matrix. Cathepsin cleaves proteins such as collagen type I,...

Cathepsin K, a member of the papain cysteine proteinase family is the predominant proteinase responsible for the resorption of the bone matrix. Cathepsin cleaves proteins such as collagen type I,...

Cathepsin K, a member of the papain cysteine proteinase family is the predominant proteinase responsible for the resorption of the bone matrix. Cathepsin cleaves proteins such as collagen type I,...

Cathepsin L (Active), Human Liver | 7539Description: Cathepsin L is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Substrates for Cathepsin L include...

3741BP | Cathepsin L (Cleaved) Blocking Peptide DataSheetAntibody Target: Cathepsin L (Cleaved) Accession #: P07154Gene ID: 115743Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: In...

K142 | Cathepsin L Activity Fluorometric Assay Kit DataSheet

6669 | Cathepsin L Antibody DataSheet

3192BP | Cathepsin L Blocking Peptide DataSheetAntibody Target: Cathepsin L (for 3192-100) Accession #: P07711Gene ID: 1514Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2...

3741 | Cathepsin L (Cleaved) Antibody DataSheet

K161 | Cathepsin L Inhibitor Screening Kit Fluorometric DataSheet

Cathepsin L is a lysosomal protease that can be secreted from the cell and is implicated to play a role in protein degradation, arthritis, apoptosis, and cancer.1135 | Cathepsin L human recombinant...

K144 | Cathepsin S Activity Fluorometric Assay Kit DataSheet

6686 | Cathepsin S Antibody DataSheet

3366RBP | Cathepsin S Blocking Peptide DataSheetAntibody Target: Cathepsin S Accession #: P25774Gene ID: 1520Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in...

K7277 | Cathepsin S human Elisa Kit DataSheet

K149 | Cathepsin S Inhibitor Screening Kit Fluorometric DataSheet

A sensitive fluorogenic substrate for Cathepsin K. This substrate is also cleaved by cathepsin B, F, L, L2/V, S as well as by malaria parasite cysteine proteases falcipain-1, -2, -3, berghepain, and...

3411 | Cathepsin V Antibody (Clone BV55-1) DataSheet

3712 | Cathepsin V Antibody DataSheet

3712BP | Cathepsin V Blocking Peptide DataSheetAntibody Target: Cathepsin VAccession #: O60911Gene ID: 1515Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in...

3412 | Cathepsin W Antibody (Clone BV39-2B) DataSheet

CTSZ, also known as cathepsin Z/X, is a relatively new cysteine protease of the papain family. Compared to other members of the papain family, CTSZ has a short proregion and unique insertions. Acting...

The Cationized-BSA (cBSA) carrier protein is prepared by modifying native BSA with excess ethylenediamine, which caps all the negatively charged carboxyl groups of BSA and introduces extra positively...

A1010 | Caveolin-1 Antibody DataSheet

CAY-10415 is a potent anti-diabetic drug of the TZD structural class. CAY-10415 lowers blood glucose levels in obese, hyperglycemic, hyperinsulinemic, and insulin-resistant KKAγ mice. It enhances the...

CAY-10441 is a potent and selective IP (prostacyclin) receptor antagonist. It displays high affinity for IP receptors. CAY-10441 antagonizes the carbaprostacyclin-induced activation of human...

CAY-10499 is a potent non-selective lipase inhibitor (IC50s = 144, 90, and 14 nM for human recombinant MAGL, HSL, and FAAH, respectively).CAY-10499 is a potent non-selective lipase inhibitor (IC50s =...

CAY-10698 | B3345Description: CCAY-10698 is an inhibitor of 12-LO (12-lipoxygenase) with an IC50 value of 5.1 µM. It displays weaker potency for 15-LO-1, 15-LO-2, and 5-LO (IC50s = >50, >40, and >200...

CAY10505 is a potent inhibitor of phosphoinositide 3-kinase (PI3K), selectively inhibiting the γ isoform with an IC₅₀ of 30 nM. It inhibits the α, β, and δ isoforms of PI3K with IC₅₀ values of 0.94,...

CAY10566 is a potent and selective stearoyl-CoA desaturase (SCD) inhibitor (IC₅₀ values of 4.5 and 26 nM in mouse and human enzymatic assays, respectively.CAY10566 is a potent and selective...

CAY10575 is an inhibitor of IKK-ε. IKK-ε is a homolog of IKK-α and IKK-β which can activate NF-κB. NF-κB is activated upon degradation of IκB following IKK-α and IKK-β phosphorylation. CAY10575 is a...

CAY10577 is an inhibitor of Casein kinase 2 (CK2) with an IC₅₀ value of 0.8 µM. CK2 is a serine/threonine-selective protein kinase which is implicated in the development of some cancers, viral...

CAY10602 is an activator of SIRT1. The sirtuins (SIRTs) are NAD+-dependent histone deacetylases. SIRT1 alters gene expression by deacetylating transcription factors such as NF-κB, p53, and FOXO...

CAY10603 is a selective inhibitor of Histone deacetylase 6 (HDAC6). The IC₅₀ for inhibition of HDAC6 is 2 pM, in vitro. CAY10603 inhibited growth of various pancreatic cell lines with IC₅₀ values...

CAY10669 is an inhibitor of the histone acetyltransferase PCAF (p300/CREB-binding protein-associated factor). The IC₅₀ for inhibition of PCAF is 662 μM. CAY10669 at 30-60 μM concentration...

CAY10683 is a potent histone deacetylase (HDAC) inhibitor isolated from the cyanobacterium Symploca. It inhibits HDAC2 and HDAC6 with IC₅₀ values of 0.119 and 434 nM, respectively. Inhibits HDAC4...

CAY10685 is an active clickable analog of the lysine acetyltransferase inhibitor 4-(4-chlorophenyl)-2-(2-cyclopentylidenehydrazinyl)thiazole (CPTH2 hydrochloride). The alkyne moiety reacts with an...

CB-103 acts as a potent Pan-NOTCH inhibitor by targeting NOTCH transcriptional activation complex. CB-103 blocks NOTCH signaling in human T cell acute lymphoblastic leukemia cancer cell lines and...

CB-1158 dihydrochloride (INCB01158 dihydrochloride) is a potent nhibitor of arginase, with IC₅₀s of 86 and 296 nM for recombinant human arginase 1 and 2, respectively.CB-1158 dihydrochloride...

CB-1158 (INCB001158) is a potent, and selective inhibitor of human arginase I (IC₅₀ = 98 nM), an immune-mediated anti-tumor agent. Displays potential for anti-tumor activity in renal cell cancer,...

CB-839 is a potent, selective, and orally bioavailable inhibitor of both splice variants of glutaminase (KGA and GAC); inhibits recombinant GAC with an IC₅₀ of

CB5083 is a potent, ATP-competitive, D2-selective, p97 inhibitor (IC₅₀ = 11 nM). In xenograft models, CB-5083 causes modulation of key p97-related pathways, induces apoptosis, and has antitumor...

6835 | CBFb polyclonal antibody DataSheet

A potent histone deacetylase (HDAC) inhibitor (ID₅₀ values of 0.01 and 0.07 μM in vitro for HDAC1 and HDAC3, respectively). CBHA also induces apoptosis in nine different neuroblastoma cell lines in...

CBL0137 is a metabolically stable curaxin that activates p53 (EC₅₀ = 0.37 μM) and inhibits NF-κB (EC₅₀ = 0.47 μM). It functionally inactivates the facilitates chromatin transcription complex (FACT),...

3960 | CBP-Tag Antibody DataSheet

3960BP | CBP-Tag Blocking Peptide DataSheetAntibody Target: CBP-tagAccession #: N/AGene ID: N/AAppearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate buffered...

CBR-5884 is a potent and selective inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH) (IC₅₀ = 33 μM) inhibiting serine synthesis from 3-phosphoglycerate in cells. CBR-5884 inhibits serine...

CBR4 belongs to the short-chain dehydrogenase/reductase family. The formation of heteroteramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity for o- and p-quinones...