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6960 | CD45RO FITC Monoclonal Antibody (Clone UCHL1) DataSheet

Membrane cofactor protein isoform 14, also known as CD46, is a type I membrane protein that has cofactor activity for inactivation of complement components C3b and C4b by serum factor I. This...

E4318 | CD47 Human Elisa Kit DataSheet

A1077 | Anti-CD47 Antibody DataSheet

CD5 is a good immunohistochemical marker for T-cells, although not as sensitive as CD3. About 76% of T-cell neoplasms are reported to express CD5, and it is also found in chronic lymphocytic...

E4551 | CD52 Human Elisa Kit DataSheet

6961 | CD54 (ICAM1) FITC Monoclonal Antibody (Clone 15.2) DataSheet

6939 | CD58 Antibody DataSheet

Macrosialin, also known as CD68, is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. It is found in cytoplasmic granules and in the cytoplasm of various...

T-cell antigen CD7, also known as CD7, is a type I transmembrane glycoprotein that is expressed on pluripotential hemopoietic cells, most human thymocytes and some peripheral blood T cells. The CD7...

6802 | CD73/NT5E Antibody (CT) DataSheet

HLA class II histocompatibility antigen gamma chain isoform b, also known as CD74, is a transmembrane protein which, on antigen presenting cells, is the invariant chain that chaperones MHC class II...

CD79B, also known as Igb and B29, is a 36 kDa transmembrane glycoprotein in the immunoglobulin superfamily. Heterodimers of CD79A and CD79B associate with a membrane bound immunoglobulin on the B...

6954 | CD8 FITC Monoclonal Antibody (Clone OKT-8) DataSheet

K4172 | CD80 Human Elisa Kit DataSheet

CD83 is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The protein may be involved in the regulation of antigen presentation. A soluble form of this...

CD84 is a membrane glycoprotein that is a member of the signaling lymphocyte activation molecule (SLAM) family. This family forms a subset of the larger CD2 cell-surface receptor Ig superfamily. The...

K4175 | CD86 Human Elisa Kit DataSheet

A1068 | CD86 Polyclonal Antibody DataSheet

CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor and...

6938 | CD9 Antibody DataSheet

3080BP | cdc/Rac Blocking Peptide DataSheetAntibody Target: cdc/Rac Accession #: NP_426359.1Gene ID: 998Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in phosphate...

3080 | cdc42/Rac Antibody DataSheet

CDE-096 is a high affinity, synthetic inactivator of plasminogen activator inhibitor-1 (PAI-1). CDE-096 binds to PAI-1 with nanomolar affinity and induces conformational changes that prevent binding...

Cyclin-dependent kinase 2-associated protein 1 (CDK2AP1), a growth suppressor that negatively regulates CDK2 activity, has been implicated in various types of cancer. This protein was found to also...

Cdk4 Inhibitor is an indolocarbazole which is a potent, selective and ATP competitive cyclin D1/CDK4 inhibitor. It has an IC₅₀ value of 76 nM. It inhibits tumor cell growth, arrests tumor cells at...

Cdk9 Inhibitor II is a potent and selective inhibitor of Cdk9 with an IC₅₀ value of 0.35 µM in vitro. It is also an inhibitor of Cdk2-cyclin E with respect to ATP, with Ki and IC₅₀ values of 13.3 µM...

CDNF is a secreted neurotrophic factor that is expressed in brain, neuronal and certain non-neuronal tissues. It has been shown to promote survival, growth and function of dopamine specific neurons...

Cediranib (AZD2171) is a tyrosine kinase inhibitor that targets vascular endothelial growth factor receptors (VEGFR) 1, 2, and 3, c-KIT, and platelet-derived growth factor receptors. Studies show...

Cerdulatinib is a novel, dual spleen tyrosine kinase (Syk) and janus kinase (JAK) inhibitor. It preferentially inhibits JAK1 and JAK3 dependent cytokine mediated signaling and functional responses in...

Cefadroxil is a semisynthetic cephalosporin antibiotic. It is active against the bacteria B. anthracis, V. cholerae, and P. multocida (MICs = 1, 2, and 4 µg/ml, respectively) among others.Cefadroxil...

Cefazolin is a broad-spectrum, first-generation cephalosporin antibiotic that is active in vitro against most Gram-positive and Gram-negative bacteria. It inhibits bacterial cell wall synthesis,...

Cefotaxime sodium is a broad spectrum third generation cephalosporin antibiotic. Cefotaxime inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the...

Cefoxitin is a second-generation cephalosporin antibiotic that has been used to treat a wide range of gram-negative and gram-positive bacteria including anaerobes. It acts by interfering with...

Cefsulodin is a third generation cephalasporin antibiotic that inhibits cell wall synthesis. It has high activity against Pseudomonas aeruginosa with no significant activity against other gram...

Contains ~10% Na2CO3. Ceftazidime is a third-generation cephalosporin and a broad-spectrum antibiotic. used to study the effect of expression, binding and inhibition of penicillin-binding proteins...

Cell-permeable. An Antioxidant, anti-inflammatory and immunosuppressive agent. Suppresses LPS-induced cytokine release in macrophages and monocytes (IC₅₀ = 40 nM for IL-1β and IL-1α, 80 nM for IL-6,...

Celecoxib is a highly selective COX-2 inhibitor and primarily inhibits prostaglandin production. Celecoxib is approximately 7.6-fold more selective for COX-2 inhibition over COX-1. This specificity...

K1442 | Cell & tissue genomic DNA extraction and purification kit DataSheet

K173 | Cell Cytotoxicity Assay Kit II WST-SRB-Crystal Violet DataSheet

The Cell Lysis Buffer is optimized for lysis of mammalian cells and tissues for caspase activity assays. The buffer is intended to use as a supplemental reagent for researchers who need to lyse large...

K307 | Cell Proliferation Assay Kit Fluorometric DataSheet

K295 | Cell Surface Protein Isolation Kit DataSheet

K921 | Cell Transformation Assay Kit Colorimetric DataSheet

K922 | Cell Transformation Assay Kit Fluorometric DataSheet

K315 | Cell-Mediated Cytotoxicity Fluorometric Assay Kit 7-AAD/CFSE DataSheet

Cellulose Acetate Syringe Filters are low protein binding syringe filters. Hence these filters are ideal for tissue culture media and sensitive biological samples filtration. Filters also contain...

Cellulose Acetate Syringe Filters are low protein binding syringe filters. Hence these filters are ideal for tissue culture media and sensitive biological samples filtration. Filters also contain...

Cellulose Acetate Syringe Filters are low protein binding syringe filters. Hence these filters are ideal for tissue culture media and sensitive biological samples filtration. Filters also contain...

Cellulose Acetate Syringe Filters are low protein binding syringe filters. Hence these filters are ideal for tissue culture media and sensitive biological samples filtration. Filters also contain...

Cellulose Acetate Syringe Filters are low protein binding syringe filters. Hence these filters are ideal for tissue culture media and sensitive biological samples filtration. Filters also contain...

Cenicriviroc is a potent inhibitor of C-C chemokine receptors CCR5 and CCR2. It is an orally bioavailable derivative of TAK-779 with potent anti-HIV-1 activity. It blocks the binding of MIP-1α and...

CENTA is a chromogenic β-lactamase substrate that is readily hydrolyzed by β-lactamases of all classes except for the Aeromonas hydrophila metalloenzyme. Useful for kinetic studies involving...

CEP-18770 is a reversible P2 threonine boronic acid inhibitor of the chymotrypsin-like activity of the proteasome. Displays anti-multimyeloma (MM) effect.CEP-18770 is a reversible P2 threonine...

CEP-28122 is a highly potent and selective orally active inhibitor of anaplastic lymphoma kinase (ALK) (IC₅₀ = 1.9 nM). Displays antitumor activity in experimental models of human cancers.CEP-28122...

CEP-32496 specific and selective inhibitor of the activity of the mutated form (V600E) of B-raf kinase. It inhibits the activation of the RAF/mitogen-activated protein kinase kinase...

CEP-33779 is a potent and orally available inhibitor of JAK2 (IC₅₀ = 1.3 nM). It displays 65-fold selectivity for JAK2 over JAK3. CEP-33779 induces regression of established colorectal tumors,...

CEP-37440 is a potent and selective dual FAK/ALK inhibitor with IC₅₀ s of 2.3 nM (FAK) and 120 nM (ALK cellular IC₅₀ in 75% human plasma). The inhibition leads to disruption of ALK- and FAK-mediated...

CEP-40783 (RDX-106) is a potent and selective inhibitor of AXL and c-Met with IC₅₀ values of 7 nM and 12 nM, respectively. In AXL-transfected 293GT cells, CEP-40783 was 27-fold more active compared...

Cephalexin is a cephalosporin antibiotic used to study the effect of expression, binding, and inhibition of PBP3 and other penicillin-binding proteins (PBPs) on bacterial cell wall mucopeptide...

Cepharanthine is an alkaloid extracted from the plant Stephania cepharantha Hayata. It shows antimalarial, antiviral, anti-inflammatory, and antitumor activities. The IC₅₀ values against different...

Ceralifimod (also known as ONO-4641), is a next-generation sphingosine 1-phosphate (S1P) receptor agonist selective for S1P receptors 1 and 5. In vitro, ONO-4641 displays highly potent agonistic...

Cercosporamide is a potent inhibitor of MAP-kinase interacting kinases (Mnk1 and Mnk2), and JAK3 (IC₅₀ values are 115, 11, and 31 nM for Mnk1, Mnk2 and JAK3, respectively). Also inhibits Pkc1. Blocks...

Cercosporin is a light-induced polyketide phytotoxin reported to produce singlet oxygen when photoactivated. Acts as a potent and specific PKC inhibitor. Competes for the phorbol binding site...

Antibiotic. Fatty acid synthase (FAS) inhibitor, reported to bind in equimolar ratio to β-keto-acyl-ACP synthase, thus inhibiting protein acylation. Produces metabolic effects similar to effects of...

K669 | Ceruloplasmin Activity Colorimetric Assay Kit DataSheet

7019 | Ceruloplasmin Antibody DataSheet

An acute-phase reactant. Increased levels are associated with normal pregnancy, rheumatoid arthritis, and cirrhosis. Decreased levels are associated with hepatolenticular degeneration (Wilson's...

Human Ceruloplasmin (CER) is officially known as ferroxidase or iron(II):oxygen oxidoreductase. CER is an enzyme synthesized in the liver containing 8 atoms of copper in its structure. Although Human...

Cetirizine is a selective histamine H1 receptor antagonist with a Ki of 6 nM. It is a highly efficacious, well-tolerated, treatment for the management of Allergic Rhinitis. Cetirizine exerts...

K595 | CETP Activity Fluorometric Assay Kit II DataSheet

3413 | CETP Antibody DataSheet

3413BP | CETP Blocking Peptide DataSheetAntibody Target: CETP Accession #: P41182Gene ID: 604Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate buffered...

K4170 | CETP Human Elisa Kit DataSheet

K594 | CETP Inhibitor Screening Kit Fluorometric II DataSheet

CFI-400945 is a potent, ATP-competitive inhibitor of PLK4 (Polo-like kinase 4) (Ki = 0.2 nM). Displays anticancer properties. PLK4 inhibition also prevents cell division and inhibits proliferation of...

cFMS Receptor Inhibitor II (BUN-60856) is a potent cell-permeable and potent CSF1R (Colony stimulating factor 1 receptor) kinase inhibitor (IC50 = 80 nM). It potently inhibits the cFMS-dependent...

cFMS Receptor Inhibitor IV is a furan carboxamide compound that is a potent, reversible, and ATP-competitive inhibitor of cFMS (Colony-stimulating Factor-1 Receptor) Tyrosine Kinase. It blocks cFMS...

5986 | CFP Antibody DataSheet

CFTR Inhibitor II, or GlyH-101, is a glycine hydrazide that selectively and reversibly blocks the CFTR channel (Ki = 4.3 µM). GlyH-101 binds to a site at the external pore of CFTR, occluding the pore...

A potent, reversible, selective, CFTR chloride channel blocker. Inhibits CFTR short-circuit current in < 2 minutes in a voltage-independent manner (Ki = ~ 300 nM). At concentrations fully inhibiting...

A potent STING ligand. Second messenger in human and mouse cells that triggers interferon production in response to cytosolic DNA. Binding to STING leads to activation of IRF3 (IFN regulatory factor...

CGI-1746 is a potent, cell-permeable, ATP-competitive BTK inhibitor (IC₅₀ = 1.9 nM). It is specific for BTK, with around 1000-fold selectivity over Tec and Src family kinases.CGI-1746 is a potent,...

3901 | CGI-58 Antibody DataSheet

3901BP | CGI-58 Blocking Peptide DataSheetAntibody Target: CGI-58Accession #: AAD34053Gene ID: 51099Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

CGK 733 is a potent and selective inhibitor of ATM/ATR with an IC50 value of ~200 nM.CGK 733 is a potent and selective inhibitor of ATM/ATR with an IC50 value of ~200 nM.B1725 | CGK733...

CGM097 is a potent and selective MDM2 inhibitor; an orally bioavailable HDM2 (human homolog of double minute 2) antagonist with potential antineoplastic activity.CGM097 is a potent and selective MDM2...

3568 | cGMP Antibody DataSheet

K372 | cGMP Direct Immunoassay Kit Colorimetric DataSheet

CGP-57380 is a cell-permeable Inhibitor of MAP-kinase interacting kinase-1 (Mnk1, MKNK1) (IC₅₀ = 2.2 μM). Displays selectivity over p38, JNK1, ERK1, ERK2, PKC and c-src family kinases.CGP-57380 is a...

Ch 55 | B3366Description: Ch 55 is a synthetic retinoid that has high affinity for RAR-α and RAR-β receptors and low affinity for cellular retinoic acid binding protein (CRABP). Ch 55 inhibits...

CH-223191 is a potent and specific aryl hydrocarbon receptor (AhR) antagonist. It blocks activation by 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) (IC₅₀ = 0.03 µM). It also blocks TCDD-mediated...

CH5132799 is an inhibitor of class I phosphatidylinositol 3-kinase (PI3K) with IC50 value of 14nM against PI3Kα.CH5132799 is an inhibitor of class I phosphatidylinositol 3-kinase (PI3K) with IC50...

CH5183284 is a selective and orally available FGFR1/2/3 inhibitor. The IC50 values of CH5183284 on the enzyme activity of FGFR1/2/3/4 were 9.3, 7.6, 22, and 290 nM, respectively.CH5183284 is a...

CH5424802 is a potent, selective, ATP-competitive inhibitor of anaplastic lymphoma kinase (ALK) (IC₅₀ = 1.9 nM). It displays potent antitumor activity against RET-rearranged non-small cell lung...

CH7057288 as a potent and selective TRK (tropomyosin receptor kinase) inhibitor that may be useful in inhibiting TRK fusion-positive cancer cell growth. CH7057288 shows selective inhibitory activity...

A fungal mycotoxin that inhibits the histone lysine methyltransferase (HKMT) SU(VAR)3-9 (IC₅₀ = 0.8 μM). Inhibits other Lys9-specific HMTs, including G9a (IC₅₀ = 2.5 μM) and DIM5 (IC₅₀ = 3 μM)...

A 10% sterile-filtered solution in water of the zwitterionic detergent CHAPS (Cat. No. 1545).A 10% sterile-filtered solution in water of the zwitterionic detergent CHAPS (Cat. No. 1545).B1322 | CHAPS...

A zwitterionic non-denaturing detergent that protects the native state of proteins, able to disrupt non-specific protein interactions and has less protein aggregation than non-ionic detergents. It is...

CHD-5 is a potent aryl hydrocarbon receptor (AhR) antagonist.CHD-5 is a potent aryl hydrocarbon receptor (AhR) antagonist.2693 | CHD-5 DataSheetAlternate Name/Synonyms:...