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Glesatinib is a potent multitargeted tyrosine kinase inhibitor. It binds to and inhibits the phosphorylation of several receptor tyrosine kinases (RTKs), including the c-Met receptor (hepatocyte...

Immunoplates for Exosome capture and quantification from human biofluids (plasma, serum, urine, saliva) and from human or mouse cell media. Transparent, white and black plates are available depending...

GlialExoPure™ Immunoplates (Exosome Isolation, plasma, fluorimetric assay) | M1024

GlialExoPure™ Immunoplates (Exosome Isolation, plasma, luminometric assay) | M1023

Cell-permeable. An anti-diabetic agent. ATP-sensitive potassium channel (KATP) blocker. Inhibits KATP currents in the pancreatic beta cells causing an increase in intracellular Ca2+ and insulin...

Glimepiride is a potent Kir6 (KATP) channel blocker and anti-diabetic agent. Inhibits pinacidil-activated cardiac Kir6 channels with an IC₅₀ of 6.8 nM. Glimepiride displays a higher potency compared...

Globosuxanthone A is a dihydroxyxanthenone isolated from Chaetomium globosum. It displays activity against several solid tumor cell lines, NCI-H460, MCF-7, SF-268, PC-3, PC-3M, LNCaP, and DU-145...

K4162 | GLP-1 Human Elisa Kit DataSheet

GLP-1 is a proglucagon-derived peptide hormone secreted primarily by intestinal L cells during feeding. Its major physiological function is stimulation of pancreatic -cells to release appropriate...

A1065 | GLP-1R Polyclonal Antibody DataSheet

GLPG-0974 is a potent FFA2 (free fatty acid receptor 2) antagonist (IC50 = 9 nM). Displays selectivity for FFA2 over FFA3. GLPG-0974 inhibits acetate-induced migration of isolated human neutrophils...

GLPG-1690 is a selective autotaxin inhibitor with potential application in idiopathic pulmonary disease (IPF).GLPG-1690 is a selective autotaxin inhibitor with potential application in idiopathic...

GLPG0634 analog is a potent and selective JAK1 inhibitor with IC₅₀ values of 10, 28, 810, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively.GLPG0634 analog is a potent and selective JAK1...

Glucagon human/mouse/rat EIA Kit | K4756

E4597 | Glucokinase Human Elisa Kit DataSheet

E4598 | Glucokinase Mouse Elisa Kit DataSheet

Glucose is phosphorylated to glucose-6-phosphate by glucokinases. This gene is alternatively spliced to generate three different forms of the enzyme; one found in the pancreas and two found in the...

Glucose is phosphorylated to glucose-6-phosphate by glucokinases. This gene is alternatively spliced to generate three different forms of the enzyme; one found in the pancreas and two found in the...

K319 | Gluconokinase GntK Activity Assay Kit Colorimetric DataSheet

The Glucose AGE BSA II was produced by reacting BSA with glucose under sterile conditions followed by extensive dialysis and purification steps. Fluorescence of AGEs was confirmed by fluorescence...

K616 | Glucose and Sucrose Colorimetric/Fluorometric Assay Kit DataSheet

K686 | Glucose Colorimetric Assay Kit II DataSheet

K606 | Glucose Colorimetric/Fluorometric Assay Kit DataSheet

K786 | Glucose Dehydrogenase Activity Colorimetric Assay Kit DataSheet

K491 | Glucose Isomerase Activity Assay Kit Colorimetric DataSheet

K788 | Glucose Oxidase Activity Colorimetric/Fluorometric Assay Kit DataSheet

K676 | Glucose Uptake Colorimetric Assay Kit DataSheet

K666 | Glucose Uptake Fluorometric Assay Kit DataSheet

K697 | Glucose-1-Phosphate Colorimetric Assay Kit DataSheet

K657 | Glucose-6-Phosphate Colorimetric Assay Kit DataSheet

K757 | Glucose-6-Phosphate Dehydrogenase Activity Colorimetric Assay Kit DataSheet

K225 | Glucose-6-Phosphate Dehydrogenase Inhibitor Screening Kit Colorimetric DataSheet

Glumetinib (SCC-244) is a potent and highly selective inhibitor of c-Met kinase (IC₅₀ = 0.42 nM). Glumetinib displays subnanomolar potency against c-Met kinase activity and high selectivity versus...

3945 | GLUT4 Antibody DataSheet

3945BP | GLUT4 Blocking Peptide DataSheetAntibody Target: GLUT4Accession #: EDL12495.1Gene ID: 20528Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

K440 | Glutamate Carboxypeptidase II Inhibitor Screening Kit Fluorometric DataSheet

K629 | Glutamate Colorimetric Assay Kit DataSheet

Glutamate Decarboxylase α is a pyridoxal 5′-phosphate dependent enzyme. GAD α catalyzes conversion of glutamate to GABA. Aberrant expressions of GAD α have been associated with diabetes and...

K729 | Glutamate Dehydrogenase Activity Colorimetric Assay Kit DataSheet

Glutaminase C-IN-1 (968) a cell-permeable, reversible inhibitor of a mitochrondrial glutaminase splice variant, glutaminase C (IC₅₀ = ~2.5 µM), which is commonly found in cancer cells. Glutaminase...

K479 | Glutaminase GLS1 Inhibitor Screening Kit Fluorometric DataSheet

K556 | Glutamine Colorimetric Assay Kit DataSheet

GLUL also known as Glutamine synthetase. It is a trimetallic enzyme containing two divalent cation sites and one monovalent cation site per subunit. GLUL is able to regulate intracellular...

6211 | Glutaredoxin 1 Antibody (Clone 28C3) DataSheet

K261 | Glutathione Colorimetric Assay Kit DataSheet

Glutathione (GSH) ethyl ester is a cell-permeable derivative of GSH that undergoes hydrolysis by intracellular esterases to release GSH. Effective transport of GSH ethyl ester has been used to...

K251 | Glutathione Fluorometric Assay Kit DataSheet

K264 | Glutathione GSH/GSSG/Total Fluorometric Assay Kit DataSheet

6214 | Glutathione Peroxidase 1 Antibody (Clone 2A10) DataSheet

K4225 | Glutathione peroxidase 1 Human Elisa Kit DataSheet

6215 | Glutathione Peroxidase 3 Antibody (Clone 55A) DataSheet

Glutathione Peroxidase 4 Antibody Clone 1H11 | 6213

K762 | Glutathione Peroxidase Activity Colorimetric Assay Kit DataSheet

K761 | Glutathione Reductase Activity Colorimetric Assay Kit DataSheet

6212 | Glutathione Reductase Antibody (Clone 2B3) DataSheet

E4623 | Glutathione Reductase GR Human Elisa Kit DataSheet

E4625 | Glutathione Reductase GR rat Elisa Kit DataSheet

E4624 | Glutathione Reductase, mitochondrial Mouse Elisa Kit DataSheet

Glutathione-Sepharose is prepared by covalently coupling glutathione to epoxy-activated 4 % cross-linked sepharose beads to form a stable thioether linkage. The coupling was optimized to give a high...

K681 | GluTracker Glucose Uptake Assay Kit Cell-Based DataSheet

GLX-351322 is a potent NADPH oxidase-4 (NOX-4) inhibitor. Displays selectivity for NOX-4 over NOX-2. GLX-351322 inhibits hydrogen peroxide production from tetracycline inducible NOX4-overexpressing...

A sterile-filtered solution (50%) of Glycerol in de-ionized water.Glycerol (50%), Sterile Solution is a sterile-filtered solution of Glycerol (50%) in deionized waterB1012 | Glycerol (50%), Sterile...

K977 | Glycerol Cell-Based Assay Kit DataSheet

K640 | Glycerol-3-Phosphate Dehydrogenase Activity Colorimetric Assay Kit DataSheet

K641 | Glycerol-3-Phosphate G3P Colorimetric Assay Kit DataSheet

K433 | Glycerophosphorylcholine Assay Kit Colorimetric/Fluorometric DataSheet

K589 | Glycine Assay Kit Fluorometric DataSheet

Glycine N-methyltransferase, also known as GNMT, catalyzes the synthesis of N-methylglycine (sarcosine) from glycine using S-adenosylmethionine (AdoMet) as the methyl donor. This protein affects DNA...

A1116 | Glycine Oxidase Antibody DataSheet

Glycine oxidase (GO) from Bacillus subtilis (EC 1.4.3.19) is a homotetrameric flavin-dependent oxidoreductase. Each GO monomer is non-covalently bound to flavin adenine dinucleotide. GO catalyzes...

K648 | Glycogen Colorimetric Assay Kit II DataSheet

K646 | Glycogen Colorimetric/Fluorometric Assay Kit DataSheet

E4609 | Glycogen Synthase Kinase GSK Mouse Elisa Kit DataSheet

E4610 | Glycogen Synthase Kinase GSK Rat Elisa Kit DataSheet

Glycoursodeoxycholic acid (GUDCA) is a glycine-conjugated form of the secondary bile acid ursodeoxycholic acid. It displays antioxidant effects in vitro in Barrett’s esophagus cells and primary...

K591 | Glyoxalase I Activity Assay Kit Colorimetric DataSheet

The glyoxalase system consists of Glyoxalase I (Glx I) and Glyoxalase II (Glx II) which is responsible for detoxifying -ketoaldehydes such as the potent and cytotoxic methylglyoxal (MG). Glx I...

K460 | Glyoxalase II Activity Kit Colorimetric DataSheet

GLYX-13 is an N-methyl-D-aspartate receptor (NMDAR) modulator that has characteristics of a glycine site partial agonist. Displays nootropic, neuroprotective and antinociceptive activity, and...

Cell-permeable. A broad spectrum matrix metalloprotease (MMP) inhibitor with Ki values of 0.4 nM, 0.5 nM, 27 nM, 3.7 nM, 0.1 nM, 0.2 nM, 3.6 nM, 13.4 nM, 0.36 nM for MMPs -1, -2, -3, -7, -8, -9, -12,...

5100 | GM-CSF Antibody DataSheet

K4772 | GM-CSF human Elisa Kit DataSheet

Human GM-CSF (Granulocyte Macrophage Colony stimulating Factor) is a potent species-specific stimulator of bone marrow cells. GM-CSF stimulates precursor cells of granulocytes, macrophages and...

Murine GM-CSF (Granulocyte Macrophage Colony stimulating Factor) is a potent species-specific stimulator of bone marrow cells. GM-CSF stimulates precursor cells of granulocytes, macrophages and...

GM-CSF, also known as granulocyte macrophage colony-stimulating factor, is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation...

Rat GM-CSF (Granulocyte Macrophage Colony stimulating Factor) is a potent species-specific stimulator of bone marrow cells. GM-CSF stimulates precursor cells of granulocytes, macrophages and...

Glia Maturation Factor-Beta (GMF-Beta) is a 17 kDa protein nerve growth factor identified as a growth and differentiation factor in the vertebrate brain.Glia Maturation Factor-Beta stimulates...

GMFG is a hematopoietic-specific protein that mediates the pluripotentiality and lineage commitment of human hematopoietic stem cells. Glia maturation factor gamma is a cytokine-responsive protein in...

K1427 | GMS Stain Kit DataSheet

GN25 blocks Snail binding to p53 and induces p53 expression in cancer cells in a KRas dependent manner. Oncogenic KRas has been shown to inhibit p53 function by inducing Snail to bind and eliminate...

GNE-477 is a potent and efficacious dual PI3K/mTOR inhibitor with IC50 of 4 nM for PI3Kα, Kiapp is 21 nM for mTOR.GNE-477 is a potent and efficacious dual PI3K/mTOR inhibitor with IC50 of 4 nM for...

GNE-0877 is a selective, brain-penetrable Leucine-rich repeat kinase 2 (LRRK2) inhibitor with a Ki of 0.7 nM. Mutations in LRRK2 are associated with Parkinson's disease. GNE-0877 inhibits LRRK2...

GNE-272 is a potent and selective in vivo probe for the bromodomains of CBP/EP300 (IC₅₀ values of 0.02, 0.03 and 13 μM for CBP, EP300 and BRD4, respectively). Displays marked antiproliferative effect...

GNE-317 is a potent and selective PI3K inhibitor with potential anticancer activity.GNE-317 is a potent and selective PI3K inhibitor with potential anticancer activity.B1716 | GNE-317...

GNE-3511 is a potent and selective zipper kinase (DLK, MAP3K12) inhibitors.GNE-3511 is a potent and selective zipper kinase (DLK, MAP3K12) inhibitors.B1341 | GNE-3511 DataSheetAlternate...

GNE-7915 is a highly potent LRRK2 kinase inhibitGNE-7915 is a highly potent LRRK2 kinase inhibitB1342 | GNE-7915 DataSheetAlternate Name/Synonyms:...

GNE-9605 is a selective, brain-penetrable Leucine-rich repeat kinase 2 (LRRK2) inhibitor with an IC₅₀ of 19 nM. Mutations in LRRK2 are associated with Parkinson's disease. GNE-9065 inhibits LRRK2...

An allosteric, non-ATP-competitive inhibitor of Bcr-Abl tyrosine kinase (IC₅₀ = 267 nM). GNF-2 inhibits proliferation and induces apoptosis in Bcr-abl-expressing cells.GNF-2 is an allosteric,...

GNF-4877 is a potent inhibitor of Dyrk1a (IC₅₀ = 6 nM) and GSK-3β (IC₅₀ = 16 nM), that promotes pancreatic β cell proliferation in rodent and human primary islets.GNF-4877 is a potent inhibitor of...

GNF-5 is a selective non-ATP competitive inhibitor of Bcr-AblGNF-5 is a selective non-ATP competitive inhibitor of Bcr-AblB1329 | GNF-5 DataSheetAlternate Name/Synonyms:...