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IL-5, also known as eosinophil differentiation factor. It regulates eosinophil growth and activation. The recombinant IL-5 is a dimeric, non-glycosylated polypeptide with 113 amino acids.4142 | IL-5...

5143 | IL-6 Antibody DataSheet

K4143 | IL-6 human Elisa Kit DataSheet

K4144 | IL-6 mouse Elisa Kit DataSheet

K4145 | IL-6 rat Elisa Kit DataSheet

IL-6 is a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B cells and T cells. Human IL-6 is a 20.9 kDa protein containing 184 amino acid residues.4143 |...

IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and...

IL-6 is a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B cells and T cells. Recombinant rat IL-6 is a 21.7 kDa protein containing 187 amino acid...

5148 | IL-7 Antibody DataSheet

K4154 | IL-7 Human Elisa Kit DataSheet

IL-7 is a hematopoietic growth factor which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of...

Interleukin-7 (IL-7) is a potent lymphoid cell growth factor that affects Pre-B, Pro-B and early T cells. It will also affect mature T cells in combination with other factors such as ConA and IL-2...

IL-7 is a hematopoietic growth factor which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of...

Human IL-8 is a 8.4 kDa protein containing 72 amino acid residues (8-79). IL-8 promotes neutrophil chemotaxis and degranulation. The 72 amino acid IL-8 is the predominant form secreted by monocytes...

IL-8 is a proinflammatory CXC chemokine that can signmal through the CXCR1 and CXCR2 receptors. It is secreted by monocytes and endothelial cells. IL-8 chemoattracts and activates neutrophils...

5149 | IL-8 Antibody DataSheet

K4169 | IL-8 Human Elisa Kit DataSheet

E4282 | IL-9 Human Elisa Kit DataSheet

Interleukin 9 (IL-9) is cytokine produced by a subgroup of helper T cells, known as Th2 cells. IL-9 signals through its receptor IL-9R to induce cell proliferation and survival. Genetically, IL-9 has...

Interleukin-9 (IL-9) is a potent lymphoid cell growth factor which stimulates the growth of certain T-cells, mast cells, and megakaryoblastic cells. Murine IL-9 is a 14.3 kDa protein containing 127...

IL-9 is an immunoregulatory cytokine produced by IL-2 activated Th2 lymphocytes. IL-9 enhances the proliferation of T lymphocytes, mast cells, erythroid precursor cells and megakaryoblastic leukemia...

IL13RA2 is closely related to Il13RA1, a subunit of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a...

IL15RA (Human) ELISA Kit | E5071-100Description: Interleukin 15 receptor, alpha subunit (IL15RA) is a subunit of the interleukin 15 receptor which is composed of three subunits IL-15R alpha, CD122,...

Interleukin-17AF (IL-17AF) is a member of the IL-17 family of proteins produced by a subset of T cells, called Th17, following stimulation with IL-23. Since IL-17AF is thought to signal through the...

Interleukin-17AF (IL-17AF) is a member of the IL-17 family of proteins produced by a subset of T cells, called Th17, following stimulation with IL-23. Since IL-17AF is thought to signal through the...

IL17B (Human) ELISA Kit | E5060-100Description: Interleukin-17B (IL17B) is a disulfide-linked homodimer of two 161 amino acid polypeptide chains. It belongs to the IL-17 family of...

Interleukin 18 (IL-18), previously known as interferon-gamma (IFN-gamma)-inducing factor, is an activator of NK cells and a co-inducer of Th1 cytokines. IL-18 is produced from Kupffer cells,...

IL18BP functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in...

IL18R1 (Human) ELISA Kit | E5067-100Description: Interleukin-18 receptor 1 (IL18R1) also known as CD218a is an interleukin receptor of the immunoglobulin superfamily. It is involved in IL18-mediated...

IL1F10 is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in...

K4229 | IL1RA/IL1RN Human Elisa Kit DataSheet

IL20RA (Human) ELISA Kit | E5073-100Description: Interleukin 20 receptor, alpha subunit (IL20RA) is a subunit for the receptor for interleukin 20, a cytokine that may be involved in epidermal...

IL28A (Human) ELISA Kit | E5069-100Description: Interleukin-28A (IL28A) is distantly related to type I interferons and the IL-10 family. Expression of IL28A is induced by viral infection which...

IL28B (Human) ELISA Kit | E5059-100Description: IL28B also known as Interferon lambda-3 is a cytokine remotely related to type I interferons and the IL-10 family. It has antiviral, antitumor and...

IL2RB (Human) ELISA Kit | E5055-100Description: Interleukin-2 receptor (IL-2R) is a heterotrimeric protein expressed on the surface of certain immune cells, such as lymphocytes, that binds and...

IL31RA (Human) ELISA Kit | E5074-100Description: Interleukin-31 receptor subunit alpha (IL31RA) is a common receptor subunit for IL6 (MIM 147620)-type cytokines. IL31RA and Oncostatin M receptor form...

IL36A (Human) ELISA Kit | E5057-100Description: Interleukin-36 alpha (IL36A) is a novel cytokine which belongs to the IL-1 family that is involved in the development of inflammatory diseases. Cells...

IL36B (Human) ELISA Kit | E5058-100Description: Interleukin‑36 beta (IL36B) belongs to the IL‑1 family of proteins (1 ‑ 3, 6). IL36B binds to and signals through the IL1RL2/IL-36R receptor which in...

IL36G (Human) ELISA Kit | E5072-100Description: Interleukin-36 gamma (IL36G) also known as interleukin-1 family member 9 (IL-1F9) is a member of interleukin IL-1 like proinflammatory cytokine family...

IL5RA (Human) ELISA Kit | E5070-100Description: Interleukin-5 receptor, alpha (IL5RA) also known as CD125 is a heterodimeric cytokine receptor. The IL5RA is a 60 kDa glycosylated protein which binds...

IL7R (Human) ELISA Kit | E5068-100Description: Interleukin-7 receptor (IL7R) is a heterodimer protein found on the surface of cells. It consists of two subunits, interleukin-7 receptor-α (CD127) and...

Cell-permeable. A marine sponge metabolite that acts as a cytoplasmic microtubule inhibitor. Induces a complete and reversible breakdown/disruption of Golgi membranes into smaller vesicular...

3423 | ILK1 Antibody DataSheet

3423BP | ILK1 Blocking Peptide DataSheetAntibody Target: ILK1 Accession #: NP_034692 Gene ID: 16202Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

3337 | ILP-2 Antibody DataSheet

3337BP | ILP-2 Blocking Peptide DataSheetAntibody Target: ILP-2 Accession #: AAK81892Gene ID: 112401Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

IM-12 is a potent and selective GSK-3β inhibitor (IC₅₀ = 53 nM). It significantly increases β-catenin levels, leads to TCF-induction and promotes neuronal differentiation in human neural progenitor...

IM156 is a bioenergetic biguanide derivative which blocks mitochondrial complex I and an activator of AMP-activated protein kinase (AMPK). It is a derivative of metformin. IM156 causes energy...

Image Distant Pcr Mix | M1138

Image Green™ 1 kb DNA Marker containing Image green DNA stain which is a non-toxic and efficient alternative DNA visualizing agent to the carcinogenic ethidium bromideM1156 | Image Green™ 1 kb DNA...

Image Green™ 100 bp DNA Marker containing Image green DNA stain which is a non-toxic and efficient alternative DNA visualizing agent to the carcinogenic ethidium bromideM1155 | Image Green™ 100 bp...

Image Ready Pcr Mix | M1129

An inhibitor of the bcr-abl tyrosine kinase. It acts by binding to the ATP binding site of bcr-abl. Imatinib also stimulates the entry of the bcr-abl tyrosine kinase into the nucleus, where it cannot...

A free base form of Imatinib Mesylate (Cat. No. 1625-100, 1000).Imatinib, Free base is a free base form of Imatinib Mesylate (Cat. No. 1625-100, 1000).2141 | Imatinib, Free base DataSheetAlternate...

IMD-0354 is a selective IKKβ inhibitor that blocks IκBα phosphorylation in NF-κB pathway. IMD0354 inhibits TNF-α induced NF-κB transcription activity with an IC50 of 1.2 uM. It has been used to study...

Imidapril is a prodrug for the active metabolite imidaprilat, an angiotensin-converting enzyme (ACE) inhibitor that suppresses the conversion of angiotensin I to angiotensin II (IC₅₀ = 2.6 nM),...

A solution (5 M) of Imidazole buffer in de-ionized water.Imidazole (5 M) solution is a solution of Imidazole in deionized waterB1014 | Imidazole (5 M) Solution DataSheetAlternate Name/Synonyms:...

An excellent buffer in the pH range of 6.2-7.8. Imidazole has a pKa of 7.0 at 20°C.Imidazole, MegaPure™ is an excellent buffer in the pH range of 6.2-7.8. Imidazole has a pKa of 7.0 at 20°C.1802 |...

Cell-permeable. Topical immune response modifier that displays anti-angiogenic, anti-viral and anti-inflammatory properties. Up-regulates IL-18 and down-regulates MMP-9 through recognition of...

Imisopasem manganese is a manganese-based non-peptidyl mimetic of the human mitochondrial manganese superoxide dismutase (MnSOD), with potential antioxidant and chemo/radioprotective activities...

’s Immobilized Catalase beads are the ideal solution for HTP preparation of samples containing hydrogen peroxide or unwanted analytes which generate hydrogen peroxide that interferes with downstream...

K286 | Immunoprecipitation IP Kit DataSheet

IMPAD1, also known as Inositol monophosphatase 3, is a member of the inositol monophosphatase family. IMPAD1 is localized to the Golgi apparatus and catalyzes the hydrolysis of phosphoadenosine...

A furanocoumarin isolated from Opopanax chironium L. Displays anticancer properties. It induces apoptosis as well as DNA fragmentation at the G1/S phase of the cell cycle. Imperatorin sensitizes...

Importazole is a 2,4-diaminoquinazoline that inhibits the function of transport receptor importin-β, likely by altering its interaction with RanGTP. Importazole prevents nuclear import of GFP-tagged...

IMR-1 (Inhibitor of Mastermind Recruitment-1), is a small molecule inhibitor that disrupts the recruitment of Mastermind-like 1 to the Notch transcriptional activation complex on chromatin, thereby...

Inauhzin is a potent SIRT inhibitor that effectively reactivates p53 by inhibiting SIRT1 activity. Inauhzin inhibits cell proliferation, induces senescence, and p53-dependent apoptosis of human...

INCB-024360 is a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor ( IC₅₀ = 10 nM); displays high selectivity over other related enzymes such as IDO2 or tryptophan 2,3-dioxygenase...

INCB057643 is a potent and selective BET inhibitor; displays more effectivity against androgen-dependent (VCaP and LNCaP) than androgen-independent (DU145 and PC3) cells with IC50 of 500 nM,...

INCB39110 is a potent JAK1 (Janus Kinase 1) inhibitor that displays anticancer properties.INCB39110 is a potent JAK1 (Janus Kinase 1) inhibitor that displays anticancer properties.B1894 | INCB39110...

Indisulam is a novel sulfonamide antitumor agent that displays potent antitumor activity in vitro and in vivo. It affects cell cycle progression in human tumor cells. Indisulam also acts as a...

Indole-3-carbinol is an anticancer phytochemical in cruciferous vegetables. It is produced by the breakdown of the glucosinolate glucobrassicin by the action of enzyme myrosinase. It induces...

K972 | Indoleamine 2,3-Dioxygenase 1 IDO1 Activity Assay Kit DataSheet

K976 | Indoleamine 2,3-Dioxygenase 1 IDO1 Inhibitor Screening Kit DataSheet

Inducible nitric oxide synthase (iNOS), also known as inflammatory nitric oxide synthase, is a calcium independent isoenzyme involved in synthesis of nitric oxide (NO). It is a soluble enzyme encoded...

3924BP | Influenza A Virus Hemagglutinin (HA) Blocking Peptide DataSheetAntibody Target: Influenza A Virus Hemagglutinin (HA) Accession #: ACF76760Gene ID: Appearance: Colorless liquidConcentration:...

K524 | Influenza Neuraminidase Inhibitor Susceptibility Assay Kit DataSheet

ING-2 AM is the membrane permeable form of the sodium indicator ING-2 (Cat. No. B3138). Masking the negative charge using non-polar, ester-linked moieties (AM ester) allows the molecule to enter...

ING-2 is a yellow-green fluorescent intracellular sodium Na⁺ indicator. It is a small, synthetic fluorochrome fused with a Na⁺-binding moiety. When Na⁺ binds to ING-2, the quenching is relieved, and...

Ingenol 3-angelate is a specific Protein Kinase C (PKC) activator and anti-cancer agent. Displays potent antileukemic activity mediated via the d isoform of PKC.Ingenol 3-angelate is a specific...

Ingenol is a diterpenoid related to phorbol that acts as a weak protein kinase C (PKC) activator that displays a Ki value of 30 μM and an ED₅₀ value of 27 μM in vitro. Most ingenol esters are...

INH6 is a potent inhibitor of Hec1/Nek2 which regulate the mitotic spindle formation together. It causes chromosome mis-alignment, apoptosis and cell death. It inhibits proliferation of MDA-MB231,...

Cell-permeable. A potent, irreversible inhibitor of poly (ADP-ribose) polymerase-1 (PARP1). Displays strong anti-neoplastic properties.Iniparib is a potent, irreversible inhibitor of poly...

INK-128 is a potent, selective and ATP-competituve mTORC1/2 inhibitor with potential anticancer properties. Displays >200-fold less selectivity towards class I PI3-K isoforms. Recently, it has been...

INO-1001 is a potent and selective inhibitor of Poly(ADP-ribose) polymerase (PARP). Shown to inhibit endogenous poly-ADP-ribosyltransferases often present in membrane preparations with minimal effect...

Inorganic pyrophosphatase, Thermostable catalyzes the hydrolysis reaction of inorganic pyrophosphate to orthophosphate. M1233 | Inorganic Pyrophosphatase Thermostable DataSheetSort Name: Inorganic...

K712 | Inosine Fluorometric Assay Kit DataSheet

INS, also known as insulin preproprotein, is a biologically inactive precursor to the biologically active endocrine hormone insulin. Insulin is an essential hormone for maintaining metabolic...

K1412 | Insect Genomic DNA Kit DataSheet

3854 | Insig1 Antibody DataSheet

3854BP | Insig1 Blocking Peptide DataSheetAntibody Target: Insig1 Accession #: NP_071787Gene ID: 64194Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

K339 | InSitu HDAC Activity Fluorometric Assay Kit DataSheet

5772 | Insulin Antibody DataSheet

Insulin human Elisa Kit | K4742

K4271 | Insulin Mouse Elisa Kit DataSheet

Recombinant Human insulin produced in E.Coli is a two chain, non-glycosylated polypeptide chain containing 51 amino acids and having a molecular mass of 5.81 kDa. Recombinant insulin is purified by...

Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen...

Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved...

An integrin ligand peptide derived from fibronectin and vitronectin. Surfaces displaying this peptide supports human embryonic stem (hES) cell adhesion but not self-renewal.Integrin Ligand peptide is...

Interferon α-2/IFNA2 Protein, Mouse Recombinant | P1751Description: Produced by macrophages and infected cells in response to viral infection, Interferon alpha-2 (also known as IFNA2) elicits...