26

An antidiabetic agent. Acts as a potent inhibitor of dipeptidyl peptidase IV (DPP IV), an enzyme that breaks down glucagon-like peptide 1 (GLP-1). Prevents the inactivation of endogenous GLP-1 and...

Linamarin is a cyanogenic glycoside defense compound produced by plants and insects. Found in cassava. Displays neurotoxic effects in rats. Linamarin induces memory and cognition deficits in rodents...

E4612 | Lincomycin Elisa Kit DataSheet

Lincomycin is an antibiotic produced by Streptomyces lincolnensis. It inhibits bacterial protein synthesis by forming cross-links within the peptidyl transferase loop region of the 23S rRNA. It is...

K902 | Link-FAST 5 Minutes DNA Ligation Kit DataSheet

A potent, small-molecule dual insulin-like growth factor-1 receptor (IGF-1R)/insulin receptor (IR) kinase inhibitor. Inhibits IGF-1R and IR kinases with IC₅₀ values of 35 nM and 75 nM, respectively...

K722 | Lipase Activity Colorimetric Assay Kit DataSheet

K723 | Lipase Activity Colorimetric Assay Kit II DataSheet

K724 | Lipase Activity Fluorometric Assay Kit III DataSheet

K216 | Lipid Extraction Kit Chloroform Free DataSheet

K580 | Lipid Oil Red O staining Kit DataSheet

K739 | Lipid Peroxidation MDA Colorimetric/Fluorometric Assay Kit DataSheet

3832 | Lipin 2 Antibody DataSheet

3832BP | Lipin 2 Blocking Peptide DataSheetAntibody Target: Lipin 2 Accession #: Q99PI5Gene ID: 64898Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

3819 | Lipocalin-2 Antibody DataSheet

3819BP | Lipocalin-2 Blocking Peptide DataSheetAntibody Target: Lipocalin-2 Accession #: P11672Gene ID: 16819Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in...

Lipocalin-2 (LCN-2), a secreted glycoprotein, is an adipokine that potentially connects obesity and its related adipose inflammation. Lipocalin-2 has also been implicated in a variety of processes...

E4313 | Lipocalin-2/NGAL Human Elisa Kit DataSheet

E4585 | Lipocalin-2/NGAL Mouse Elisa Kit DataSheet

E4586 | Lipocalin-2/NGAL Rat Elisa Kit DataSheet

K577 | Lipolysis 3T3-L1 Colorimetric Assay Kit DataSheet

K581 | Lipolysis Adipocyte Colorimetric/Fluorometric Assay Kit DataSheet

K438 | Lipopolysaccharide LPS Isolation Kit DataSheet

In a normal fasting individual, Lp(a) concentrations range from 20-760 mg/L. Lp(a) levels are associated with premature atherosclerosis; thus elevated Lp(a) is considered a high risk factor for...

K721 | Lipoprotein Lipase Activity Fluorometric Assay Kit DataSheet

In a normal fasting individual, low density lipoprotein concentrations range from 2.0 - 3.5 g/L. LDL constitutes 50% of the total lipoprotein mass in plasma and is the major carrier of cholesterol...

HDL is the vehicle for reversed cholesterol transport and estrification, serving as a scavenger for free cholesterol during intravascular catabolism of lipoproteins. HDL levels are inversely...

HDL is the vehicle for reversed cholesterol transport and estrification, serving as a scavenger for free cholesterol during intraVascular catabolism of lipoproteins. HDL levels are inversely...

IDL functions in the endogenous lipid transport system. It is the particle resulting from the interaction of VLDL and lipoprotein lipase. When IDL receives cholesteryl esters from HDL, it is...

In a normal fasting individual, VLDL concentrations range from 0.5 - 2.0 g/L. VLDL transports triglycerides synthesized by the liver to sites of energy storage and utilization.4933 | Lipoproteins...

LDL levels strongly correlate with coronary heart disease. In a normal fasting individual, low density lipoprotein concentrations range from 2.0 - 3.5 g/L. LDL constitutes 50% of the total...

IDL functions in the endogenous lipid transport system. It is the particle resulting from the interaction of VLDL and lipoprotein lipase. When IDL receives cholesteryl esters from HDL, it is...

In a normal fasting individual, VLDL concentrations range from 0.5 - 2.0 g/L. VLDL transports triglycerides synthesized by the liver to sites of energy storage and utilization.7855 | Lipoproteins...

K978 | Lipoxygenase Activity Assay Kit Fluorometric DataSheet

A potent inhibitor of ferroptosis. Liproxstatin-1 suppresses ferroptosis in human cells and in an ischemia/reperfusion-induced tissue injury model in mice. Knockout of glutathione peroxidase 4 (Gpx4)...

K1255 | LiqBiopsy Tumor Exosome DNA Kit I DataSheet

K1256 | LiqBiopsy Tumor Exosome DNA Kit II DataSheet

K1254 | LiqBiopsy Tumor Exosome RNA Kit DataSheet

Liraglutide is a highly potent, long-acting glucagon-like peptide 1 (GLP-1) receptor agonist (EC₅₀ = 61 pM). It increases cAMP accumulation in CHO cells expressing the human GLP-1 receptor. Inhibits...

Lisinopril is a potent angiotensin converting-Enzyme (ACE) inhibitor (IC₅₀ = 4.7 nM). The administration of lisinopril can lower the diastolic and systolic blood pressure and higher the heart rate...

LIT-927 is a locally and orally active CXCL12 neutraligand (Ki = 267 nM for CXCL12-TR binding). Displays anti-inflammatory effect in a murine model of allergic airway hypereosinophilia.LIT-927 is a...

K545 | Lithium Assay Kit Colorimetric DataSheet

Lithocholic acid (LCA) is a hydrophobic secondary bile acid that is primarily formed in the intestine by the bacterial 7-α dehydroxylation of chenodeoxycholic acid. Acts as a detergent to solubilize...

K501 | Live-Dead Cell Staining Kit DataSheet

K502 | Live/Dead Cell Viability Assay Kit for Mammalian Cells DataSheet

3338 | Livin Antibody DataSheet

LIX is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. LIX is a chemoattractant for neutrophils. The two naturally...

LJH685 is a potent and specific RSK (p90 ribosomal S6 kinase) inhibitor. Inhibits RSK1, 2, and 3 biochemical activities with IC₅₀ values of 4 to 13 nM.LJH685 is a potent and specific RSK (p90...

LJI308 is a potent pan-RSK inhibitor, with IC₅₀ values of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively.LJI308 is a potent pan-RSK inhibitor, with IC₅₀ values of 6 nM, 4 nM, and 13 nM...

3950 | LKB1 Antibody DataSheet

3950BP | LKB1 Blocking Peptide DataSheetAntibody Target: LKB1 Accession #: ACE73833.1Gene ID: 20869Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

A Stat3 phosphorylation inhibitor. LLL12 inhibits STAT3 phosphorylation (Tyr705) and STAT3 activities and down-regulates STAT3 downstream targets; inhibits proliferation, colony formation, and cell...

LLY-283 is a potent, selective protein arginine methyltransferase 5 (PRMT5) inhibitor (IC50 = 22 nM). It is selective for PRMT5 over a panel of 32 methyltransferases, including PRMT4, -6, and -7 at 1...

LLY-507 is a potent, cell-permeable, small molecule inhibitor of SMYD2 (IC₅₀ = 15 nM), a lysine N-methyltransferase. It has been shown to inhibit p53 lysine monomethylation in KYSE-150 esophageal...

LM22B-10 is an activator of Tropomyosin-receptor kinase neurotrophin receptors TrkB and TrkC. It binds to TrkB and TrkC in a dose-dependent manner at concentrations of 250 nM-2000 nM. It increases...

LMK235 is a HDAC inhibitor, previously shown to be a novel and specific inhibitor of human HDAC4 and 5, with IC50 values of 0.49 μM (A2780) and 0.32 μM (A2780 CisR).LMK235 is a HDAC inhibitor,...

5302 | LMX1B Antibody (CT) DataSheet

Loganin is an antioxidant and cytochrome P450 substrate. Displays potent free-radical-scavenging activity. Selective β-secretase and COX-1 inhibitor. Shows neuroprotective effects against...

3785 | LOK Antibody DataSheet

Lomeguatrib is a potent inhibitor of DNA repair protein O6-Methylguanine-DNA methyltransferase (MGMT) and related mammalian proteins. PaTrin-2 displays nanomolar activity in vitro and in vivo...

Lomitapide is a small molecule that lowers total cholesterol levels by inhibiting microsomal triglyceride transfer protein (MTTP) and preventing the assembly of apoB-containing lipoproteins and VLDL...

Lonafarnib (SCH 66336) is a selectively farnesyltransferase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM, respectively.Lonafarnib (SCH 66336) is a selectively...

Longdaysin is a potent modulator of circadian rhythm. It slows the circadian clock both in cultured mammalian cells and zebrafish. It inhibits the protein kinases CKIδ, CKIα, ERK2, and CDK7...

Lonidamine is a derivative of indazole-3-carboxylic acid that inhibits glycolysis by the inactivation of hexokinase, an enzyme that catalyzes glucose as the first step in glycolysis. Also blocks CFTR...

Loperamide is an antidiarrheal agent that acts as a non-selective Ca²⁺ channel blocker. At nanomolar concentrations (Ki = 2 nM), Loperamide binds to µ-opioid receptors. Also acts as an...

A protease inhibitor with high specificity for HIV-1 protease. Inhibition of HIV-1 protease (responsible for protein cleavage), results in selectively inhibiting the cleavage of HIV gag and gag-pol...

Losartan is a selective, non-peptide angiotensin II type 1 (AT1) receptor antagonist. Clinically useful antihypertensive agent. Inhibits collagen I synthesis.Losartan is a selective, non-peptide...

Losmapimod is a potent and selective p38 MAPK inhibitor with pKis of 8.1 and 7.6 for p38α and p38β, respectively. Displays no significant activity for p38γ, p38δ (

A cholesterol lowering drug and a competitive inhibitor of HMG-CoA (3-hydroxy-3-methylglutaryl coenzyme A) reductase, a rate limiting enzyme in cholesterol synthesis. Blocks the production of...

3659R | LOX-1 Antibody DataSheet

3659RBP | LOX-1 Blocking Peptide DataSheetAntibody Target: LOX-1 Accession #: P78380Gene ID: 4973Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

LOXO-101 is a potent, ATP-competitive TRK inhibitor with IC₅₀s in low nanomolar range for inhibition of all TRK family members in binding and cellular assays, with 100-fold selectivity over other...

LOXO-101 is a potent, ATP-competitive TRK inhibitor with IC₅₀s in low nanomolar range for inhibition of all TRK family members in binding and cellular assays, with 100-fold selectivity over other...

LOXO-195 is a potent and selective TRK (tropomyosin-related-kinase) inhibitor, with potential anticancer activity. LOXO-195 specifically targets and binds to TRK, including the fusion proteins...

Loxoprofen sodium is a non-steroidal anti-inflammatory drug (NSAD) with analgesic and anti-pyretic properties. It acts as a nonselective COX inhibitor with IC50s of 6.5 and 13.5 μM for COX-1 and...

A guanosine derivative that acts as a selective ligand for Toll-like receptor 7 (TLR7) via IFN. Activates natural killer cells and primes cytolytic precursor cells for activation by IL-2.Loxoribine...

LP99 is an inhibitor of BRD9 and BRD7 bromodomains. LP99 inhibits the interactions of both BRD7 and BRD9 with histones H3.3 and H4, with IC₅₀ values in the low micromolar range in bioluminescence...

3947 | LPL Antibody DataSheet

3947BP | LPL Blocking Peptide DataSheetAntibody Target: LPL Accession #: AAH81836.1Gene ID: 24539Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

LRIG1, also known as leucine-rich repeats and immunoglobulin-like domains 1 is a pan-negative regulator of the epidermal growth factor receptor (EGFR) signaling pathway. In studies with ErbB family...

3714 | LRP-5/6 Antibody DataSheet

3714BP | LRP-5/6 Blocking Peptide DataSheetAntibody Target: LRP-5/6 Accession #: O75197Gene ID: 4041Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

3801BP | LRP-5/6 Blocking Peptide DataSheetAntibody Target: LRP-5/6 Accession #: Gene ID: Appearance: Colorless liquidConcentration: 1.0 mg/mlFormulation: 50 µg (1 mg/ml) in phosphate buffered saline...

K4228 | LRRK2 Human Elisa Kit DataSheet

LRRK2-IN-1 is a potent inhibitor of Leucine-rich repeat kinase 2 (LRRK2). Mutations in LRRK2 are associated with Parkinson's disease. LRRK2-IN-1 inhibits wild-type and G2019S mutant LRRK2 with IC₅₀...

The mono, di- and trimethylation of particular lysine residues in histone tails (e.g. histone H3 lysine-4 (H3K4), H3K9, H3K27, H3K36, H4K20) are implicated in the transmission of heritable epigenetic...

3129 | LSD1/AOF2 Antibody DataSheet

3129BP | LSD1/AOF2 Blocking Peptide DataSheetAntibody Target: LSD1/AOF2Accession #: NP_001123570.1Gene ID: 500579Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in...

LSN-2814617 is a potent and selective positive allosteric modulator at the mGlu5 receptor (EC50 = 24 nM). It acts as a potent and selective potentiator of human and rat mGlu₅ receptors in vitro,...

LTURM-34 is a potent DNA-PK inhibitor (IC₅₀ = 34 nM). Displays 170-fold selectivity for DNA-PK over PI3-K. Attenuates proliferation of a wide range of tumor cell lines in vitro.LTURM-34 is a potent...

Lu AF21934 is a brain-penetrating positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu4), that reduces the harmaline-induced hyperactivity.Lu AF21934 is a brain-penetrating...

Lubiprostone is a bicyclic fatty acid metabolite analog of Prostaglandin E1 that activates ClC-2 and CFTR chloride channels. It has been suggested that lubiprostone opens CFTR or both CFTR and ClC-2...

3848 | Luciferase Antibody DataSheet

K801 | Luciferase Reporter Assay Kit DataSheet

Lucigenin is a chemiluminescent probe for the detection of superoxide in biological systems. It has been used for the generation of chemiluminescence in the presence of a reductant and oxygen...

Luminol is a useful probe that displays chemiluminescence upon oxidation. Horseradish peroxidase (HRP), combined with hydrogen peroxide as an activator, causes luminescent peroxidation of luminol...

Lumiracoxib is a non-steroidal anti-inflammatory drug (NSAID) that acts as a potent and selective cyclooxygenase-2 (COX-2) inhibitor. Displays anti-inflammatory properties.Lumiracoxib is a...

Lungkine is a CXC chemokine that is expressed in lung epithelial cells and, to a lesser extent, in certain fetal tissues. No human homolog has been identified and a specific cell surface receptor has...

Lupeol is a dietary triterpene that displays potent potent anti-inflammatory, anticarcinogenic, antimutagenic, and antimalarial activity. It suppresses the growth of hepatocellular carcinoma cell...

Luteinizing Hormone [LH] human Elisa Kit | K7426