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PD-168393 is a cell-permeable, irreversible inhibitor of EGFR kinase activity (IC₅₀ = 0.70 nM). PD-168393 decreases the production of TNF-α and phosphorylation of ERK1/2 and p38 induced by LPS in...

Programmed death 1 ligand 1 (PD-L1) also known as cluster of differentiation (CD274) or B7 homolog 1 (B7-H1), is a member of the growing B7 family of immune molecules and is involved in the...

WL12 peptide is a highly specific programmed death ligand 1 (PD-L1) binding peptide that can be used as a PET (positron emission tomography) imaging agent for PD-L1. PD-L1 is an immune checkpoint...

K4155 | PD-L1/CD274 Human Elisa Kit DataSheet

PD0332991 is a highly specific inhibitor of Cdk4 (IC₅₀ = 11 nM) and Cdk6 (IC₅₀ = 16 nM). Displays selectivity for Cdk4/6 over a panel of 34 additional protein kinases (IC₅₀ values are > 10 μM)...

A highly potent ATP-noncompetitive MEK inhibitor. It inhibits MEK with an in vitro IC₅₀ of 1-1.3 nM. It does not inhibit other kinases. Highly recommended tool to inhibit MKK1 or MKK1 plus MKK5...

PD318088 is an allosteric and non-ATP competitive MEK1/2 inhibitor.PD318088 is an allosteric and non-ATP competitive MEK1/2 inhibitor.B1697 | PD318088 DataSheetAlternate Name/Synonyms: PD318088; PD...

Programmed cell death 1 ligand 2, also known as PDCD1LG2, is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction...

3956 | PDE3B Antibody DataSheet

3956BP | PDE3B Blocking Peptide DataSheetAntibody Target: PDE3B Accession #: Gene ID: Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate buffered saline...

Platelet Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle and connective tissue. PDGF, which is composed of a dimer of two chains...

Recombinant Mouse Platelet Derived Growth Factor-AA is a disulfide linked dimer comprised of 2 polypeptide chains of 126 amino acids each, with a dimeric molecular weight of 28.9 kDa. Belonging to a...

Platelet Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle and connective tissue. PDGF, which is composed of a dimer of two chains...

5488 | PDGF-BB Antibody DataSheet

Platelet Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle and connective tissue. PDGF, which is composed of a dimer of two chains...

Recombinant mouse Platelet Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle and connective tissue. PDGF, which is composed of a...

The platelet-derived growth factor (PDGF) family of heparin-binding growth factors consists of five known members, denoted PDGF-AA, PDGF-BB, PDGF-AB, PDGF-CC and PDGF-DD. The mature and active form...

6787 | PDGFR Antibody (Clone # 275CT1) DataSheet

PDGFRb (platelet-derived growth factor receptor b) is a member of the PDGFR family of membrane receptors with intrinsic tyrosine kinase activity. PDGFRb deficient mice are hemorrhagic, severely...

5601 | PDI (Protein Disulfide Isomerase) Antibody DataSheet

Pyruvate phosphate dikinase, PPDK, (E.C. 2.7.9.1) is found in certain microorganisms and plants. PPDK catalyzes the interconversion of AMP, PPi, and phosphoenolpyruvate (PEP) to ATP, Pi, and pyruvate...

3449 | PDK1 Antibody DataSheet

3449BP | PDK1 Blocking Peptide DataSheetAntibody Target: PDK1 Accession #: Q9Z2A0Gene ID: 18607Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate buffered...

The initial steps in insulin signal transduction occur at the plasma membrane and lead to the activation of phosphatidylinositide (PtdIns) 3-kinase and the formation of PtdIns(3,4,5,)P3 in the inner...

An antioxidant and an inhibitor of NF-kB; prevents induction of nitric oxide synthase (NOS) by inhibiting translation of NOS mRNA; induces apoptosis in rat smooth muscle cells and inhibits apoptosis...

’s PE-Cy5 is a tandem FRET conjugate dye, combining R-PE (240 kDa) and a cyanine dye (Cy5). The PE can be excited at 488 nm and functions as an efficient energy donor for the Cy5 which acts as an...

6680 | PEDF Antibody DataSheet

PEDF is a noninhibitory serpin with neurotrophic, anti-angiogenic, and anti-tumorigenic properties. PEDF is a 50,000 dalton glycoprotein created and secreted in many tissues all the way through the...

Pigment epithelium-derived factor (PEDF) is a 47 kDa secreted glycoprotein that belongs to the non-inhibitory serpin family group. PEDF is widely expressed in adult and fetal tissues, including...

Peficitinib is a potent JAK inhibitor, with IC₅₀s of 3.9, 5.0, 0.7 and 4.8 nM for JAK1, JAK2, JAK3 and Tyk2, respectively. Peficitinib inhibits IL-2-induced proliferation of rat splenocytes (IC₅₀ =...

K904 | PEG Virus Precipitation Kit DataSheet

Pelitinib is a pan-ErbB tyrosine kinase inhibitor with potential anticancer activity. Pelitinib irreversibly binds covalently to epidermal growth factor receptors (EGFR) ErbB-1, -2 and -4, thereby...

Cell-permeable. A natural product isolated from the roots of Piper Nigrum. Modulator of the sensory neuron function to induce tingling parethesia. Excellent stable model compound for sensory studies...

Pemafibrate free acid (K877) is a selective peroxisome proliferator-activated receptor-α (PPAR-α) modulator and a next-generation PPAR-α agonist. It activated PPAR-α, PPAR-γ, and PPAR-δ with EC₅₀...

Pemetrexed is a high affinity dihydrofolate reductase (DHFR) inhibitor (Ki = 7 nM). Also inhibits thymidylate synthase, AICART and glycinamide ribonucleotide formyltransferase (Ki values are 109 nM,...

Pemigatinib is a potent and selective inhibitor of the fibroblast growth factor receptor (FGFR) types 1, 2, and 3 (FGFR1/2/3), with potential antineoplastic activity. Pemigatinib binds to and...

Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections. It displays activity against multiple laboratory...

Penicillide is an inhibitor of Acyl-Coenzyme A cholesterol acyltransferase (ACAT), Calpain and Oxytocin receptor. It has shown to have growth inhibition properties in plants and displays anticancer,...

Penicillin is a broad-spectrum β-lactam antibiotic. It binds to penicillin binding proteins (PBP). PBP catalyzes the synthesis of peptidoglycan, which is an important component of the bacterial cell...

Penicillin G potassium is a member of the β-lactam antibiotics. β-Lactams interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBP’s are...

Penicillin G sodium is a member of the β-lactam antibiotics. β-Lactams interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBP’s are...

Pentostatin is an irreversible inhibitor of adenosine deaminase (Ki = 2.5 pM). Pentostatin is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell leukemia. It...

Pentraxin 3 (PTX3) is the prototypic member of the long pentraxin family sharing the C-terminal domain with short pentraxins and containing a unique N-terminal domain. Pentraxin 3 is produced and...

Pentylenetetrazole is a circulatory and respiratory stimulant. It is a central nervous system modulator used to experimentally induce seizures in animals. It acts as an antagonist of GABAa receptors...

K365 | PEP Colorimetric/Fluorometric Assay Kit DataSheet

3949 | PEPCK-C Antibody DataSheet

3949BP | PEPCK-C Blocking Peptide DataSheetAntibody Target: PEPCK-C Accession #: AAH37629.1Gene ID: 18534Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in...

K446 | Pepsin/Pepsinogen Activity Assay Kit Fluorometric DataSheet

An inhibitor of acid proteases (aspartyl peptidases), e.g. pepsin, rennin, and cathepsin D. The inhibitor is highly selective and does not inhibit thiol proteases, neutral proteases, or serine...

3188 | Perforin Antibody (Clone ?G9) DataSheet

3188R | Perforin Antibody DataSheet

3188RBP | Perforin Blocking Peptide DataSheetAntibody Target: Perforin Accession #: NP_059026Gene ID: 50669Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in...

Belongs to an alkylphospholipid class of antineoplastic compounds that display potent antiproliferative activity in several in vitro and in vivo human tumor models. Perifosine induces apoptotic cell...

3948 | Perilipin A Antibody DataSheet

3948BP | Perilipin A Blocking Peptide DataSheetAntibody Target: Perilipin A Accession #: EDL07054.1Gene ID: 103968Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in...

Perindopril is a potent, brain-permeable angiotensin-converting enzyme (ACE) inhibitor (IC₅₀ = 1.05 nM). Unlike the other ACE inhibitors, inhibits tumor growth in hepatocellular carcinoma cells due...

K1433 | Periodic Acid Schiff Diastase Stain Kit DataSheet

K4760 | Periostin/OSF-2 human Elisa Kit DataSheet

K4762 | Periostin/OSF-2 mouse Elisa Kit DataSheet

Periostin was originally isolated as a osteoblast-specific factor that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and...

Periostin was originally isolated as a osteoblast-specific factor that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and...

K772 | Peroxidase Activity Colorimetric/Fluorometric Assay Kit DataSheet

6158 | Peroxiredoxin 1 Antibody (9D2) DataSheet

6159 | Peroxiredoxin II Antibody (1E8) DataSheet

6161 | Peroxiredoxin IV Antibody (3A1) DataSheet

6162 | Peroxiredoxin V Antibody (3F11) DataSheet

6163 | Peroxiredoxin VI Antibody (4A3) DataSheet

Perphenazine is a dopamine receptor antagonist. It binds to Dopamine receptors D₂, D₃ and D₄ with Ki values of 0.56 nM, 0.43 nM and 28.5 nM respectively. It also binds to serotonin receptors 5-HT1A,...

Persephin is a disulfide-linked homodimer neurotrophic factor structurally related to GDNF, Artemin, and Neurturin. These proteins belong to the cysteine-knot family of growth factors that assume...

Persephin is a disulfide-linked homodimer neurotrophic factor structurally related to GDNF, Artemin, and Neurturin. These proteins belong to the cysteine-knot family of growth factors that assume...

PES (Polyethersulfone) Syringe Filters are low protein binding to minimize interaction with your sample and maximize recovery. It is ideal for pre-filtration and filtration of buffers and culture...

PES (Polyethersulfone) Syringe Filters are low protein binding to minimize interaction with your sample and maximize recovery. It is ideal for pre-filtration and filtration of buffers and culture...

PES (Polyethersulfone) Syringe Filters are low protein binding to minimize interaction with your sample and maximize recovery. It is ideal for pre-filtration and filtration of buffers and culture...

PES (Polyethersulfone) Syringe Filters are low protein binding to minimize interaction with your sample and maximize recovery. It is ideal for pre-filtration and filtration of buffers and culture...

PES (Polyethersulfone) Syringe Filters are low protein binding to minimize interaction with your sample and maximize recovery. It is ideal for pre-filtration and filtration of buffers and culture...

PES (Polyethersulfone) Syringe Filters are low protein binding to minimize interaction with your sample and maximize recovery. It is ideal for pre-filtration and filtration of buffers and culture...

PES (Polyethersulfone) Syringe Filters are low protein binding to minimize interaction with your sample and maximize recovery. It is ideal for pre-filtration and filtration of buffers and culture...

PES (Polyethersulfone) Syringe Filters are low protein binding to minimize interaction with your sample and maximize recovery. It is ideal for pre-filtration and filtration of buffers and culture...

PES (Polyethersulfone) Syringe Filters are low protein binding to minimize interaction with your sample and maximize recovery. It is ideal for pre-filtration and filtration of buffers and culture...

PES (Polyethersulfone) Syringe Filters are low protein binding to minimize interaction with your sample and maximize recovery. It is ideal for pre-filtration and filtration of buffers and culture...

PES (Polyethersulfone) Syringe Filters are low protein binding to minimize interaction with your sample and maximize recovery. It is ideal for pre-filtration and filtration of buffers and culture...

PES (Polyethersulfone) Syringe Filters are low protein binding to minimize interaction with your sample and maximize recovery. It is ideal for pre-filtration and filtration of buffers and culture...

PES (Polyethersulfone) Syringe Filters are low protein binding to minimize interaction with your sample and maximize recovery. It is ideal for pre-filtration and filtration of buffers and culture...

PES (Polyethersulfone) Syringe Filters are low protein binding to minimize interaction with your sample and maximize recovery. It is ideal for pre-filtration and filtration of buffers and culture...

PES (Polyethersulfone) Syringe Filters are low protein binding to minimize interaction with your sample and maximize recovery. It is ideal for pre-filtration and filtration of buffers and culture...

PES (Polyethersulfone) Syringe Filters are low protein binding to minimize interaction with your sample and maximize recovery. It is ideal for pre-filtration and filtration of buffers and culture...

PES (Polyethersulfone) Syringe Filters are low protein binding to minimize interaction with your sample and maximize recovery. It is ideal for pre-filtration and filtration of buffers and culture...

PES (Polyethersulfone) Syringe Filters are low protein binding to minimize interaction with your sample and maximize recovery. It is ideal for pre-filtration and filtration of buffers and culture...

PES (Polyethersulfone) Syringe Filters are low protein binding to minimize interaction with your sample and maximize recovery. It is ideal for pre-filtration and filtration of buffers and culture...

PES (Polyethersulfone) Syringe Filters are low protein binding to minimize interaction with your sample and maximize recovery. It is ideal for pre-filtration and filtration of buffers and culture...

PES (Polyethersulfone) Syringe Filters are low protein binding to minimize interaction with your sample and maximize recovery. It is ideal for pre-filtration and filtration of buffers and culture...

PES (Polyethersulfone) Syringe Filters are low protein binding to minimize interaction with your sample and maximize recovery. It is ideal for pre-filtration and filtration of buffers and culture...

PES (Polyethersulfone) Syringe Filters are low protein binding to minimize interaction with your sample and maximize recovery. It is ideal for pre-filtration and filtration of buffers and culture...

PES (Polyethersulfone) Syringe Filters are low protein binding to minimize interaction with your sample and maximize recovery. It is ideal for pre-filtration and filtration of buffers and culture...

PES (Polyethersulfone) Syringe Filters are low protein binding to minimize interaction with your sample and maximize recovery. It is ideal for pre-filtration and filtration of buffers and culture...

PES (Polyethersulfone) Syringe Filters are low protein binding to minimize interaction with your sample and maximize recovery. It is ideal for pre-filtration and filtration of buffers and culture...

PES (Polyethersulfone) Syringe Filters are low protein binding to minimize interaction with your sample and maximize recovery. It is ideal for pre-filtration and filtration of buffers and culture...

Pexmetinib (ARRY-614) is a potent inhibitor of cytokine synthesis, via the dual inhibition of p38 mitogen-activated protein kinase (MAPK), and Tie2/Tek receptor tyrosine kinase.Pexmetinib (ARRY-614)...

PF-03394197 is potent and selective Janus kinase (JAK) inhibitor. It inhibits JAK family members with an IC₅₀ of 10-99 nM being most potent against JAK1 (IC₅₀ = 10 nM). PF-03394197 does not inhibit a...

PF-03814735 is an ATP-competitive inhibitor of Aurora kinases A and B with IC₅₀values of 0.8 and 0.5 nM respectively. It has shown to block cytokinesis, inhibit cellular proliferation in many tumor...