4-CPPC | B3278

4-CPPC is a potent, reversible and selective small molecule inhibitor of the pro-inflammatory protein macrophage migration inhibitory factor-2 (a.k.a. MIF-2 or D-DT) (IC50 = 27 µM). 4-CPPC displays17-fold selectivity for MIF-2 versus MIF-1. MIF-2 is member of the MIF cytokine superfamily.

4-CPPC is a potent, reversible and selective small molecule inhibitor of the pro-inflammatory protein macrophage migration inhibitory factor-2 (a.k.a. MIF-2 or D-DT) (IC50 = 27 µM). 4-CPPC displays17-fold selectivity for MIF-2 versus MIF-1. MIF-2 is member of the MIF cytokine superfamily.

B3278 | 4-CPPC DataSheet

Alternate Name/Synonyms: 4-(3-Carboxyphenyl)-2,5-pyridinedicarboxylic acid 4CPPC

Appearance: Crystalline solid

Formulation:

CAS Number: 29553-70-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₄H₉NO₆

Molecular Weight: 287.23

Cell-Permeable?: True

Purity: ≥98% by HPLC

Solubilities:

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A pro-inflammatory protein macrophage migration inhibitory factor-2 (MIF-2) inhibitor

MDL Number:

PubChem CID: 893698

SMILES: O=C(C1=NC=C(C(O)=O)C(C2=CC=CC(C(O)=O)=C2)=C1)O

InChi: InChI=1S/C14H9NO6/c16-12(17)8-3-1-2-7(4-8)9-5-11(14(20)21)15-6-10(9)13(18)19/h1-6H,(H,16,17)(H,18,19)(H,20,21)

InChi Key: O=C(C1=NC=C(C(O)=O)C(C2=CC=CC(C(O)=O)=C2)=C1)O