5-Iodotubercidin | B2721

5-Iodotubercidin is a potent adenosine kinase inhibitor (IC₅₀ = 26 nM). 5-Iodotubercidin initiates glycogen synthesis in isolated hepatocytes by causing inactivation of phosphorylase and activation of glycogen synthase. 5-Iodotubercidin also acts as an activator for p53 and favors tumor suppression and may serve as a potential chemotherapeutic agent.

5-Iodotubercidin is a potent adenosine kinase inhibitor (IC₅₀ = 26 nM). 5-Iodotubercidin initiates glycogen synthesis in isolated hepatocytes by causing inactivation of phosphorylase and activation of glycogen synthase. 5-Iodotubercidin also acts as an activator for p53 and favors tumor suppression and may serve as a potential chemotherapeutic agent.

B2721 | 5-Iodotubercidin DataSheet

Alternate Name/Synonyms: 7-Iodo-7-deazaadenosine 4-Amino-5-iodo-7-(β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine NSC-113939 5-Iodotubericidin NSC113939

Appearance: Off-white solid

Formulation:

CAS Number: 24386-93-4

Structure Available?: TRUE

Peptide sequence:

Salt Form: FALSE

Molecular Formula: C₁₁H₁₃IN₄O₄

Molecular Weight: 392.15

Cell-Permeable?: TRUE

Purity: ≥90% by HPLC

Solubilities: >15 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A potent adenosine kinase inhibitor

MDL Number: MFCD00055131

PubChem CID: 97297

SMILES: O[C@H]([C@H](O)[C@@H](CO)O3)[C@@H]3N1C2=C(C(N)=NC=N2)C(I)=C1

InChi: InChI=1S/C11H13IN4O4/c12-4-1-16(10-6(4)9(13)14-3-15-10)11-8(19)7(18)5(2-17)20-11/h1,3,5,7-8,11,17-19H,2H2,(H2,13,14,15)/t5-,7-,8-,11-/m1/s1

InChi Key: WHSIXKUPQCKWBY-IOSLPCCCSA-N