Ac-WEHD-pNA | B2282

Ac-WEHD-pNA is a useful colorimetric substrate for group I caspases (caspase-1, -4, and -5). Cleavage of the substrate by a caspase releases pNA, which can be detected by its absorbance at 405 nm.

Ac-WEHD-pNA is a useful colorimetric substrate for group I caspases (caspase-1, -4, and -5). Cleavage of the substrate by a caspase releases pNA, which can be detected by its absorbance at 405 nm.

B2282 | Ac-WEHD-pNA DataSheet

Alternate Name/Synonyms: Caspase-1 substrate (chromogenic), Caspase-5 substrate (chromogenic); Ac-Trp-Glu-His-Asp-paranitroanilide

Appearance: Yellow solid

Formulation: N/A

CAS Number: N/A

Structure Available?: Yes

Peptide sequence: Ac-Trp-Glu-His-Asp-pNA

Salt Form: No

Molecular Formula: C₃₄H₃₇N₉O₁₁

Molecular Weight: 747.7

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>10 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A Group I caspase substrate

MDL Number: N/A

PubChem CID: 44135315

SMILES: CC(=O)NC(CC1=CNC2=CC=CC

InChi: InChI=1S/C34H37N9O11/c1-18(44)38-26(12-19-15-36-24-5-3-2-4-23(19)24)33(51)40-25(10-11-29(45)46)31(49)41-27(13-21-16-35-17-37-21)34(52)42-28(14-30(47)48)32(50)39-20-6-8-22(9-7-20)43(53)54/h2-9,15-17,25-28,36H,10-14H2,1H3,(H,35,37)(H,38,44)(H,39,50)(H,40,51)(H,41,49)(H,42,52)(H,45,46)(H,47,48)

InChi Key: FDGCMTAKGVLJGO-UHFFFAOYSA-N