ACE (F940) polyclonal Antibody | BS3485

ACE (F940) polyclonal Antibody | BS3485 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200

Background: Angiotensin-converting enzyme (ACE) is a carboxy-terminal dipeptidyl exo-peptidase that converts Angiotensin I to the potent vasopressive hormone, Angiotensin II. There are two isoforms of ACE, the pulmonary ACEP and the testicular ACET. ACEP is a glycoprotein expressed in vascular endothelial cells of the lung, liver, adrenal cortex, pancreas, kidney and spleen. The ACET isoform is expressed exclusively in adult testis by developing sperm cells, specifically, late pachytene spermatocytes. Additionally, ACE inactivates bradykinin, a vasodepressor peptide, and is involved in fluid/electrolyte homeostasis.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ACE (F940) polyclonal Antibody detects endogenous levels of Angiotensin-converting enzyme protein.

Molecular Weight: ~ 160 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Angiotensin-converting enzyme; Short name=ACE; Dipeptidyl carboxypeptidase I; CD143; ACE1; DCP; DCP1; Angiotensin Converting Enzyme 1

Immunogen: Synthetic peptide, corresponding to amino acids 920-950 of Human ACE.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: