ACE polyclonal Antibody | BS90020

ACE polyclonal Antibody | BS90020 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Application: WB IHC FC

Application Range: WB:1:500-1:2,000 IHC:1:100-1:500 FC:1:50-1:100

Background: Angiotensin-converting enzyme (ACE) is a carboxy-terminal dipeptidyl exo-peptidase that converts Angiotensin I to the potent vasopressive hormone, Angiotensin II. There are two isoforms of ACE, the pulmonary ACEP and the testicular ACET. ACEP is a glycoprotein expressed in vascular endothelial cells of the lung, liver, adrenal cortex, pancreas, kidney and spleen. The ACET isoform is expressed exclusively in adult testis by developing sperm cells, specifically, late pachytene spermatocytes. Additionally, ACE inactivates bradykinin, a vasodepressor peptide, and is involved in fluid/electrolyte homeostasis. Although it bears significant sequence homology to ACE, ACE2 shows a more restricted pattern of expression. ACE is expressed ubiquitously throughout the vasculature while ACE2 is expressed only in cardiac, renal and testicular cells.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: ACE polyclonal Antibody detects endogenous levels of ACE protein.

Molecular Weight: 160 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: ACE, DCP, DCP1, ACE 1, ACE, ACE T, ACE, ACE1, Angiotensin converting enzyme somatic isoform, Angiotensin converting enzyme testis specific isoform, Angiotensin I converting enzyme 1, Angiotensin I converting enzyme, Angiotensin I converting enzyme peptidyl dipeptidase A 1, angiotensin I converting enzyme peptidyl-dipeptidase A 1 transcript, Angiotensin-converting enzyme, Carboxycathepsin, CD 143, CD143, CD143 antigen, DCP 1, DCP, DCP1, Dipeptidyl carboxypeptidase 1, Dipeptidyl carboxypeptidase I, Kininase II, MGC26566, MVCD3, Peptidase P, Peptidyl dipeptidase A, soluble form, Testicular ECA,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: