ADAMTS2 Antibody | 13-548

ADAMTS2 Antibody | 13-548 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant protein of mouse ADAMTS2

Research Area: Cancer, Cell Cycle, Signal Transduction

Tested Application: WB

Application: WB: 1:500 - 1:2000

Specificiy: N/A

Positive Control 1: A375

Positive Control 2: U-87MG

Positive Control 3: THP-1

Positive Control 4: Rat thymus

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 120kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: ADAM-TS 2, ADAM-TS2, ADAMTS-2, PC I-NP, PCINP, pNPI, A disintegrin and metalloproteinase with thrombospondin motifs 2, a disintegrin and metalloproteinase with thrombospondin repeats, a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 2, procollagen I/II amino propeptide-processing enzyme, procollagen N-endopeptidase, procollagen N-proteinase

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature procollagen N-proteinase. This proteinase excises the N-propeptide of the fibrillar procollagens types I-III and type V. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.