Adavivint | B2437

Adavivint is a potent and selective Wnt pathway inhibitor with an EC₅₀ of 3 nM in vitro; induces hMSC differentiation into mature, functional chondrocytes and decreases cartilage catabolic marker levels.

Adavivint is a potent and selective Wnt pathway inhibitor with an EC₅₀ of 3 nM in vitro; induces hMSC differentiation into mature, functional chondrocytes and decreases cartilage catabolic marker levels.

B2437 | Adavivint DataSheet

Alternate Name/Synonyms:

Appearance: Crystalline solid

Formulation:

CAS Number: 1467093-03-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₉H₂₄FN₇O

Molecular Weight: 505.56

Cell-Permeable?: True

Purity: ≥98% by HPLC

Solubilities: >20 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line:

MDL Number:

PubChem CID: 135565709

SMILES: CC(C)CC(=O)NC1=CN=CC(=C1)C2=CC3=C(C=C2)NN=C3C4=NC5=C(N4)C=NC=C5C6=CC(=CC=C6)F

InChi: InChI=1S/C29H24FN7O/c1-16(2)8-26(38)33-21-10-19(12-31-13-21)17-6-7-24-22(11-17)28(37-36-24)29-34-25-15-32-14-23(27(25)35-29)18-4-3-5-20(30)9-18/h3-7,9-16H,8H2,1-2H3,(H,33,38)(H,34,35)(H,36,37)

InChi Key: AQDWDWAYVBQMAM-UHFFFAOYSA-N