Description
Adavivint is a potent and selective Wnt pathway inhibitor with an EC₅₀ of 3 nM in vitro; induces hMSC differentiation into mature, functional chondrocytes and decreases cartilage catabolic marker levels.
Adavivint is a potent and selective Wnt pathway inhibitor with an EC₅₀ of 3 nM in vitro; induces hMSC differentiation into mature, functional chondrocytes and decreases cartilage catabolic marker levels.
Alternate Name/Synonyms:
Appearance: Crystalline solid
Formulation:
CAS Number: 1467093-03-3
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₉H₂₄FN₇O
Molecular Weight: 505.56
Cell-Permeable?: True
Purity: ≥98% by HPLC
Solubilities: >20 mg/ml DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line:
MDL Number:
PubChem CID: 135565709
SMILES: CC(C)CC(=O)NC1=CN=CC(=C1)C2=CC3=C(C=C2)NN=C3C4=NC5=C(N4)C=NC=C5C6=CC(=CC=C6)F
InChi: InChI=1S/C29H24FN7O/c1-16(2)8-26(38)33-21-10-19(12-31-13-21)17-6-7-24-22(11-17)28(37-36-24)29-34-25-15-32-14-23(27(25)35-29)18-4-3-5-20(30)9-18/h3-7,9-16H,8H2,1-2H3,(H,33,38)(H,34,35)(H,36,37)
InChi Key: AQDWDWAYVBQMAM-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
25 months |