451 Recombinant Proteins and Cell culture
AMBP | Bikunin (mice) | AS04 040
- SKU:
- 451-AS04 040
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Description
AMBP | Bikunin (mice) | AS04 040 | Gentaur UK, US & Europe Distribution
Immunogen: Recombinant mouse bikunin purified from baculovirus infected insect cell cultures
Host: Rabbit
Conjugation: N/A
Clonality: Polyclonal
Isotype: N/A
Purity: Serum
Format: Lyophilized
Tested Application: ELISA (ELISA), Immunohistochemistry (IHC), Western blot (WB)
Related Products: AS04 039 | Anti-rat bikunin, rabbit antibodiesAS06 173 | Anti-human bikunin, rabbit antibodiesSecondary antibodies
Recommended Dilutions: 1 : 2000 (ELISA ), Assay dependent dilution (IHC)
Molecular weight: Free bikunin appears as a smear between 60-80 kDa, because the protein core carries sulfated proteoglycans.The most common bikunin complexes are called pre-alpha-inhibitor (PaI) and inter-alpha-inhibitor (IaI) and appears as approximately 120 and 180 kDa.
Confirmed Reactivity: Mouse
Predicted Reactivity: Rat
Not reactive in: No confirmed exceptions from predicted reactivity are currently known
Additional Information: N/A
Background: Bikunin is a Kunitz-type protease inhibitor synthesized in the liver. The AMBP gene resides in the lipocalin cluster and encodes alpha-1-microglobulin together with a Kunitz-type proteinase inhibitor, bikunin. The gene is translated into the alpha-1-microglobulin-bikunin precursor, which is subsequently cleaved and the two proteins are secreted to the blood separately. Bikunin exhibits anti-inflammatory activity in protection against cancer and inflammation.
Reconstitution: For reconstitution add 200 µl of sterile water
Storage: Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
TAIR Nnumbre: N/A
Category: Other proteins
Research Area: Immunology