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Androgen Receptor Antibody | 6710

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SKU:
26-6710-100-GEN
Availability:
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£1,168.00

Description

Androgens exhibit a wide range of effects on the development, maintenance and regulation of male phenotype and reproductive physiology in males. The androgen receptor (AR) is a member of the steroid superfamily of ligand-dependent transcription factors. ARs bind active testosterone (T) and dihydrotestosterone (DHT). The rates of association and dissociation of T are about 3 times more rapid than those of DHT. This difference in binding kinetics may account for the different physiological effects of T and DHT. Androgen binding results in an at least 6-fold increase in androgen receptor stability.

6710 | Androgen Receptor Antibody DataSheet

Antibody Target: AR

Target Alternative Name: AR; DHTR; NR3C4; Androgen receptor; Dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4

Tag Line: Polyclonal Antibody to detect AR in human and mouse samples

Category: AR

Host: Rabbit

Isotype: Rabbit IgG

Species Reactivities: Human, Mouse

Immunogen Sequence: This Androgen Receptor (ANDR) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 365-392 amino acids from human Androgen Receptor (ANDR).

Accession #: P10275

Gene ID: ANDR

Appearance: Colorless liquid

Form: Liquid

Concentration: N/A

Formulation: 100 µl of antibody in PBS with 0.09% (W/V) sodium azide

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Application: Western blot, IHC

Positive Control: Western blot: HeLa and mouse brain lysate, IHC: human liver tissue

Application And Usages: Western blot: ~1:1000, IHC: ~1:10-1:50

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: Verified

Immunocytochemistry Verified: Verified

Immunofluorescence Verified: Not Verified

Immunoprecipitation Verified: Not Verified

FACS Verified:

ELISA Verified: Not Verified

ChIP Verified: Not Verified

Dot Blot Verified:

Flow Cytometry Verified: Not Verified

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Additional Information

Size:
100 uL
Storage Condition:
-20°C
Shipping Condition:
Gel Pack
Shelf Life:
12 months
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