26
Androgen Receptor Antibody | 6710
- SKU:
- 26-6710-100-GEN
- Availability:
- Usually shipped in 5 working days
Description
Androgens exhibit a wide range of effects on the development, maintenance and regulation of male phenotype and reproductive physiology in males. The androgen receptor (AR) is a member of the steroid superfamily of ligand-dependent transcription factors. ARs bind active testosterone (T) and dihydrotestosterone (DHT). The rates of association and dissociation of T are about 3 times more rapid than those of DHT. This difference in binding kinetics may account for the different physiological effects of T and DHT. Androgen binding results in an at least 6-fold increase in androgen receptor stability.
6710 | Androgen Receptor Antibody DataSheet
Antibody Target: AR
Target Alternative Name: AR; DHTR; NR3C4; Androgen receptor; Dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4
Tag Line: Polyclonal Antibody to detect AR in human and mouse samples
Category: AR
Host: Rabbit
Isotype: Rabbit IgG
Species Reactivities: Human, Mouse
Immunogen Sequence: This Androgen Receptor (ANDR) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 365-392 amino acids from human Androgen Receptor (ANDR).
Accession #: P10275
Gene ID: ANDR
Appearance: Colorless liquid
Form: Liquid
Concentration: N/A
Formulation: 100 µl of antibody in PBS with 0.09% (W/V) sodium azide
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Application: Western blot, IHC
Positive Control: Western blot: HeLa and mouse brain lysate, IHC: human liver tissue
Application And Usages: Western blot: ~1:1000, IHC: ~1:10-1:50
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: Verified
Immunocytochemistry Verified: Verified
Immunofluorescence Verified: Not Verified
Immunoprecipitation Verified: Not Verified
FACS Verified:
ELISA Verified: Not Verified
ChIP Verified: Not Verified
Dot Blot Verified:
Flow Cytometry Verified: Not Verified
Additional Information
Size: |
100 uL |
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
12 months |