Angiostatin Human | 4919

Angiostatin is a proteolytic fragment of plasminogen constituting kringles 1 - 4. It is a potent angiogenesis inhibitor and the inhibition of angiogenesis by angiostatin is directly related to inhibiting the proliferation of endothelial cells. Human Angiostatin significantly inhibits bFGF-induced endothelial cell proliferation and migration at concentrations ranging from 300 nM – 1.0 µM.

4919 | Angiostatin Human DataSheet

Biomolecule/Target: N/A

Synonyms: Angiostatin K1-4, Angiostatin Kringles 1-4

Alternates names: Angiostatin K1-4, Angiostatin Kringles 1-4, plasminogen

Taglines: An endogenous angiogenesis inhibitor

NCBI Gene ID #:

NCBI Gene Symbol: TNFSF13B

Gene Source: Human

Accession #: D4AAC1

Recombinant: No

Source: Human Plasma

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 20.7 kDa

Concentration: 7.0-8.0 mg/ml

Appearance: Liquid

Physical form description: In 20 mM HEPES, 150 mM NaCl, pH 7.4

Reconstitution Instructions: Reconstitute in sterile HO to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers or stored at 4°C for 1 week or –20°C for future use.

Amino acid sequence: N/A