Anti- EPCAM Antibody | FNab09783

Anti- EPCAM Antibody | FNab09783 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Protein A+G purification

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 3C8

Isotype: IgG1

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Epithelial cell adhesion molecule (EpCAM, CD326) is a type I transmembrane glycoprotein that functions as a homophilic, epithelial-specific intercellular cell-adhesion molecule. In addition to cell adhesion, EpCAM is also involved in cellular signaling, cell migration, proliferation, and differentiation. EpCAM is highly expressed on most carcinomas and therefore of potential use as a diagnostic and prognostic marker for a variety of carcinomas, and has become a therapeutic target. (PMID: 20837599; 19249674; 21576002; 22647938)

Immunogen: epithelial cell adhesion molecule

synonyms: GA733-2, M1S2, M4S1, MIC18, TACSTD1, TROP1

Molecular weight (observed) : 36 kDa

Reactivity Species: Human

Tested Application: ELISA, IHC

Recomended Dillution : WB: 1:1000-1:10000; IHC: 1:50-1:500

Research Area: Stem Cells, Immunology, Signal Transduction, Cancer