Anti-IL12RB1 Antibody | A1772

The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The lack of expression of this gene was found to result in the immunodeficiency of patients with severe mycobacterial and Salmonella infections. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

A1772 | Anti-IL12RB1 Antibody DataSheet

Antibody Target: Interleukin-12 receptor subunit beta-1

Target Alternative Name: CD212, I12R1, IL-12 receptor beta component, IL-12 receptor subunit beta-1, IL-12R subunit beta-1, IL-12R-beta-1, IL12RB, IMD3, Interleukin 12 receptor beta 1 chain, Interleukin-12 receptor subunit beta-1, mgC34454

Tag Line: Polyclonal antibody to detect IL12RB1 in Human samples.

Category: Immunology

Host: Rabbit

Isotype: IgG

Species Reactivities: Human

Immunogen Sequence: Recombinant protein of human IL12RB1

Accession #: P42701

Gene ID: 3594

Appearance: Colorless liquid

Form: Liquid

Concentration: 0.1 mg/ml

Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3

Purification: Affinity purification

Application: Immunohistochemistry (IHC), ELISA

Positive Control:

Application And Usages: IHC 1:25-1:100

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: False

Immunocytochemistry Verified: False

Immunofluorescence Verified: False

Immunoprecipitation Verified: False

FACS Verified: False

ELISA Verified: False

ChIP Verified: False

Dot Blot Verified: False

Flow Cytometry Verified: False