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Anti-IL12RB1 Antibody | A1772
- SKU:
- 26-A1772-100-GEN
- Availability:
- Usually shipped in 5 working days
Description
The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The lack of expression of this gene was found to result in the immunodeficiency of patients with severe mycobacterial and Salmonella infections. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
A1772 | Anti-IL12RB1 Antibody DataSheet
Antibody Target: Interleukin-12 receptor subunit beta-1
Target Alternative Name: CD212, I12R1, IL-12 receptor beta component, IL-12 receptor subunit beta-1, IL-12R subunit beta-1, IL-12R-beta-1, IL12RB, IMD3, Interleukin 12 receptor beta 1 chain, Interleukin-12 receptor subunit beta-1, mgC34454
Tag Line: Polyclonal antibody to detect IL12RB1 in Human samples.
Category: Immunology
Host: Rabbit
Isotype: IgG
Species Reactivities: Human
Immunogen Sequence: Recombinant protein of human IL12RB1
Accession #: P42701
Gene ID: 3594
Appearance: Colorless liquid
Form: Liquid
Concentration: 0.1 mg/ml
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Application: Immunohistochemistry (IHC), ELISA
Positive Control:
Application And Usages: IHC 1:25-1:100
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: False
Immunocytochemistry Verified: False
Immunofluorescence Verified: False
Immunoprecipitation Verified: False
FACS Verified: False
ELISA Verified: False
ChIP Verified: False
Dot Blot Verified: False
Flow Cytometry Verified: False
Additional Information
Size: |
100 uL |
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
12 months |