710
Anti- PPARA Antibody | FNab06663
- SKU:
- 710-FNab06663-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- PPARA Antibody | FNab06663 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC) . Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.
Immunogen: peroxisome proliferator-activated receptor alpha
synonyms: hPPAR, NR1C1, PPAR, PPAR alpha, PPARA
Molecular weight (observed) : 52-55 kDa
Reactivity Species: Human
Tested Application: ELISA, WB, IF, IHC
Recomended Dillution : WB: 1:200-1:1000; IP: 1:200-1:1000 ; IHC: 1:50-1:200
Research Area: Signal Transduction, Metabolism, Cardiovascular, Developmental biology, Neuroscience