Anti- PRKCQ Antibody | FNab10092

Anti- PRKCQ Antibody | FNab10092 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors.

Immunogen: PRKCQ

synonyms: PRKCQ, PRKCT, nPKC-theta, protein kinase C theta

Molecular weight (observed) : 85 kDa

Reactivity Species: Human

Tested Application: ELISA, IHC

Recomended Dillution : IHC: 1:50 - 1:200

Research Area: Cell Division and Proliferation, Signal Transduction, Metabolism, cancer, Immunology