710
Anti- PRKCQ Antibody | FNab10092
- SKU:
- 710-FNab10092-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- PRKCQ Antibody | FNab10092 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors.
Immunogen: PRKCQ
synonyms: PRKCQ, PRKCT, nPKC-theta, protein kinase C theta
Molecular weight (observed) : 85 kDa
Reactivity Species: Human
Tested Application: ELISA, IHC
Recomended Dillution : IHC: 1:50 - 1:200
Research Area: Cell Division and Proliferation, Signal Transduction, Metabolism, cancer, Immunology