26
Anti-Pyruvate Carboxylase Antibody | A2020
- SKU:
- 26-A2020-100-GEN
- Availability:
- Usually shipped in 5 working days
Description
This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyze the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.
A2020 | Anti-Pyruvate Carboxylase Antibody DataSheet
Antibody Target: Pyruvate Carboxylase
Target Alternative Name: Pyruvate carboxylase mitochondrial; Pyruvic carboxylase; PCB
Tag Line: Affinity purified rabbit polyclonal antibody to detect Pyruvate Carboxylase expression in human, mouse, rat bovine, chicken, monkey, porcine, sheep and zebrafish samples
Category: Primary antibody
Host: Rabbit
Isotype: IgG
Species Reactivities: Bovine, Sheep, Zebrafish, Porcine, Rat, Chicken, Monkey, Mouse, Human
Immunogen Sequence: KLH-conjugated synthetic peptide targeting a sequence within the center region of human Pyruvate Carboxylase.
Accession #: P11498
Gene ID: 5091
Appearance: Colorless liquid
Form: Liquid
Concentration:
Formulation: In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide
Purification: Affinity purified
Application: Western Blotting
Positive Control:
Application And Usages: WB 1:500 - 1:1000
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: True
Immunocytochemistry Verified: False
Immunofluorescence Verified: False
Immunoprecipitation Verified: False
FACS Verified: False
ELISA Verified: False
ChIP Verified: False
Dot Blot Verified: False
Flow Cytometry Verified: False
Additional Information
Size: |
100 uL |
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
12 months |