Description
APC Anti-Mouse CD366/Tim-3 Antibody[RMT3-23] | E-AB-F1192E | Gentaur UK, US & Europe Distribution
Category: Flowcytometry Antibody
Synonyms: TIM3, TIMD3,HAVcr-2,TIMD-3
Swissprot Code: Q8TDQ0
Application: FCM
Reactivity: Human
Host: Mouse
Isotype: Mouse IgG1, κ
Research Areas: Cancer, Immunology
Backgroun: CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.
Concentration: N/A
Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Immunogen: N/A
Buffer: PBS with 0.05% Proclin300, 1% BSA
Purification Method: N/A
Dilution: N/A
Clone: RMT3-23
Conjugation: APC
Moleculair Weight(Calculated): N/A
Moleculair Weight(Observed): N/A