Bad Antibody| F42760-0.08ML/F42760-0.4ML

Bad Antibody| F42760-0.08ML/F42760-0.4ML | Gentaur UK, US & Europe Distribution

Background: Bad is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: N/A

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: WB, IHC, ELISA

Application Details: Western blot: 1:1000, IHC (Paraffin): 1:10-1:50

Application Note: Titration of the Bad antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This Bad antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 53-81 from the human protein was used as the immunogen for this Bad antibody.

Storage: Aliquot the Bad antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A