Bak Antibody| F42652-0.08ML/F42652-0.4ML/R32246

Bak Antibody| F42652-0.08ML/F42652-0.4ML/R32246 | Gentaur UK, US & Europe Distribution

Background: BAK belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BAK localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: IHC, WB, ELISA

Application Details: IHC (Paraffin): 1:50-1:100, Western blot: 1:1000

Application Note: Titration of the Bak antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This Bak antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 56-91 from the human protein was used as the immunogen for this Bak antibody.

Storage: Aliquot the Bak antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A