BNIP3 Antibody| F42817-0.08ML/F42817-0.4ML/R30236

BNIP3 Antibody| F42817-0.08ML/F42817-0.4ML/R30236 | Gentaur UK, US & Europe Distribution

Background: NIP3 is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. NIP3 contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein is known to induce apoptosis, even in the presence of BCL2.

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human, Mouse

Predicted Spacies Reactivity: N/A

Application: IF, WB, IHC, ELISA

Application Details: Western blot: 1:1000, Immunofluorescence: 1:50-1:100, IHC (Paraffin): 1:50-1:100

Application Note: Titration of the BNIP3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This BNIP3 antibody is available for research use only.

Purity: Purified

Immunogen: A portion of amino acids 152-187 from the human protein (BH3 domain) was used as the immunogen for this BNIP3 antibody.

Storage: Aliquot the BNIP3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A